Identification of Aichi Virus Infection by Measurement of Immunoglobulin Responses in an Enzyme-Linked Immunosorbent Assay

Yamashita, Teruo; Ito, Masanao; Tsuzuki, Hideaki; Sakae, Kenji

doi:10.1128/jcm.39.11.4178-4180.2001

Cited by 41 publications

(24 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Related human kobuviruses, the pathogenic Aichi viruses, have been associated with gastroenteritis (3,30,63,77,83,(95)(96)(97)(98), while other kobuviruses have been detected worldwide in pigs and cows with diarrhea (51, 81) as well as in mouse and canine feces (45,64,78). KoV-SewKTM (GenBank accession number JQ898342) was 6,939 nucleotides (nt) long and shared ϳ82% nucleotide sequence identities to human Aichi virus, canine kobuvirus, and murine kobuvirus over its genome (see Fig.…”

Section: Figmentioning

confidence: 99%

High Variety of Known and New RNA and DNA Viruses of Diverse Origins in Untreated Sewage

Marine

Wang

et al. 2012

J Virol

243

213

View full text Add to dashboard Cite

g Deep sequencing of untreated sewage provides an opportunity to monitor enteric infections in large populations and for highthroughput viral discovery. A metagenomics analysis of purified viral particles in untreated sewage from the United States (San Francisco, CA), Nigeria (Maiduguri), Thailand (Bangkok), and Nepal (Kathmandu) revealed sequences related to 29 eukaryotic viral families infecting vertebrates, invertebrates, and plants (BLASTx E score, <10 ؊4 ), including known pathogens (>90% protein identities) in numerous viral families infecting humans (Adenoviridae, Astroviridae, Caliciviridae, Hepeviridae, Parvoviridae, Picornaviridae, Picobirnaviridae, and Reoviridae), plants (Alphaflexiviridae, Betaflexiviridae, Partitiviridae, Sobemovirus, Secoviridae, Tombusviridae, Tymoviridae, Virgaviridae), and insects (Dicistroviridae, Nodaviridae, and Parvoviridae). The full and partial genomes of a novel kobuvirus, salivirus, and sapovirus are described. A novel astrovirus (casa astrovirus) basal to those infecting mammals and birds, potentially representing a third astrovirus genus, was partially characterized. Potential new genera and families of viruses distantly related to members of the single-stranded RNA picorna-like virus superfamily were genetically characterized and named Picalivirus, Secalivirus, Hepelivirus, Nedicistrovirus, Cadicistrovirus, and Niflavirus. Phylogenetic analysis placed these highly divergent genomes near the root of the picorna-like virus superfamily, with possible vertebrate, plant, or arthropod hosts inferred from nucleotide composition analysis. Circular DNA genomes distantly related to the plantinfecting Geminiviridae family were named Baminivirus, Nimivirus, and Niminivirus. These results highlight the utility of analyzing sewage to monitor shedding of viral pathogens and the high viral diversity found in this common pollutant and provide genetic information to facilitate future studies of these newly characterized viruses.

show abstract

Section: Figmentioning

confidence: 99%

High Variety of Known and New RNA and DNA Viruses of Diverse Origins in Untreated Sewage

Marine

Wang

et al. 2012

J Virol

243

213

View full text Add to dashboard Cite

show abstract

“…This virus is a new member of the family Picornaviridae and is classified in a new genus, Kobuvirus (9,15). The detection of AiV in stool samples collected from nonbacterial-gastroenteritis outbreaks due to oyster consumption was documented in Asia (14,16,19) and in Europe (1,7). Moreover, this virus was recently identified in oysters implicated in a gastroenteritis outbreak in France (6).…”

mentioning

confidence: 99%

Aichi Virus IgG Seroprevalence in Tunisia Parallels Genomic Detection and Clinical Presentation in Children with Gastroenteritis

Sdiri-Loulizi

Hassine

Bour

et al. 2010

Clin Vaccine Immunol

View full text Add to dashboard Cite

Aichi virus has been described as a novel causative agent of gastroenteritis in humans. In this study, we report the seroprevalence distribution of Aichi virus in Tunisia. A panel of 1,000 sera was screened by applying an enzyme-linked immunosorbent assay for immunoglobulin G specific for Aichi virus. A considerable prevalence (92%) of antibody to Aichi virus was found across all age groups. The specific anti-Aichi virus antibodies increased with age, from a high rate (68.8%) in children under 10 years old to about 100% in persons more than 60 years old. We found a statistically significant increase in levels of antibody to Aichi virus according to the age of patients. Immunoglobulin M antibodies were detected among five children. A high frequency of Aichi virus monoinfections in hospitalized children with severe gastroenteritis was previously observed in Tunisia. Aichi virus causes diarrhea with dehydration, fever, and vomiting. This work is the first to establish a correlation between the high seroprevalence of specific Aichi virus antibodies, clinical presentation, and a high frequency of isolation of Aichi virus by genomic characterization in stools of children suffering from gastroenteritis. Our data show the importance and emerging character of Aichi virus in the viral etiology of pediatric gastroenteritis.

show abstract

“…Its presence in stool samples collected from nonbacterial gastroenteritis outbreaks, especially due to oyster consumption, has been documented in Japan (12,15,16), Germany (4), and France (1). Moreover, the presence of Aichi virus was reported in oyster samples during a French outbreak of gastroenteritis occurring after oyster consumption (3).…”

mentioning

confidence: 99%

“…In the Tunisian pediatric population, the frequency of detection of Aichi virus was then relatively higher than usually observed. Aichi virus has been proposed as an etiologic agent of oyster-related gastroenteritis outbreaks (11,12,15,16), but the almost systematic presence of mixed infections with other viruses led us to consider Aichi virus an indicator of infection rather than the only causative agent of gastroenteritis (1). However, the high incidence of monoinfections observed in our study supported the idea that Aichi virus is a pathogenic agent responsible for gastroenteritis, although at levels far below norovirus and rotavirus, which are the main agents.…”

mentioning

confidence: 99%

Detection and Genomic Characterization of Aichi Viruses in Stool Samples from Children in Monastir, Tunisia

et al. 2009

View full text Add to dashboard Cite

show abstract

Identification of Aichi Virus Infection by Measurement of Immunoglobulin Responses in an Enzyme-Linked Immunosorbent Assay

Cited by 41 publications

References 12 publications

High Variety of Known and New RNA and DNA Viruses of Diverse Origins in Untreated Sewage

High Variety of Known and New RNA and DNA Viruses of Diverse Origins in Untreated Sewage

Aichi Virus IgG Seroprevalence in Tunisia Parallels Genomic Detection and Clinical Presentation in Children with Gastroenteritis

Detection and Genomic Characterization of Aichi Viruses in Stool Samples from Children in Monastir, Tunisia

Contact Info

Product

Resources

About