Identification of asthma risk factors in Mexico City in an International Study of Asthma and Allergy in Childhood survey

Abstract

The International Study of Asthma and Allergy in Childhood (ISAAC) has assessed the prevalence of asthma, as well as the factors related to the disease in different countries. The aim of this study was to identify asthma risks factors in Mexico City. Data were obtained from questionnaires of children participating in a phase 3b ISAAC survey. Two thousand ninety-eight boys and 2008 girls were recruited in the 6- to 7-year-old group and 3243 boy and 3333 girls were recruited in the 13- to 14-year-old group. Logistic regression was used to determine the asthma risks factors. In the logistic regression for cumulative and current asthma prevalence, the variables allergic rhinitis and atopic dermatitis were the most important risk factors with the highest odds ratios (OR > 1.5; p < 0.05). The use of antibiotics and paracetamol in the first 12 months of life were related to cumulative asthma in both genders in the 6- to 7-year-old group. Contact of pregnant mother with farm animals was positively related with cumulative asthma in boys in the 6- to 7-year-old group. The main factors associated with the cumulative and current prevalence of asthma in both age groups were atopic dermatitis and allergic rhinitis. Future interventions for the prevention and early diagnosis and treatment could be focused in the natural history of the atopic march.

Prevalence of allergic disorders among the population in the city of Mashhad, Northeast Iran

“…The differences in the prevalence of both atopy and asthma due to geographical variations have been reported. A family history of asthma in firstdegree relatives, low educational level, low family income, overcrowding, smoking at home, degree of urbanization, living in large cities, and various variables related to indoor air were probably associated with respiratory symptoms (Cooper et al 2006;Del-Rio-Navarro et al 2006;Dinmezel et al 2005;Kawada 2004;McIntire et al 2004;Petronella and Conboy-Ellis 2003;Tsuang et al 2003). The process of industrialization of some cities has left a legacy of a widespread and often poorly controlled environment which is widely believed to have adverse implications for health, in particular for respiratory diseases (McIntire et al 2004;Monteil et al 2005;Petronella and Conboy-Ellis 2003).…”

Early-life antibiotic use is associated with wheezing among children with high atopic risk: a prospective European study

“…Within the past decade several studies have suggested that early-life exposure to antibiotics is associated with the etiology of childhood asthma [9,10]. Marra et al [11] did a systematic review study and found that the pooled OR from retrospective studies was significantly stronger than the prospective studies (OR ¼ 2.85; 95%CI 2.07-3.85 versus OR ¼ 1.12; 0.88-1.42).…”

Multidisciplinary approach to management of maternal asthma (MAMMA [copyright]): the PROTOCOL for a randomized controlled trial

“…Asthma guidelines around the world strongly recommend that women continue their asthma medications during pregnancy to maintain adequate control [7,8,12-18]. However, women are still choosing to cease their asthma medications during pregnancy, many without consulting their doctors [19-21].…”