2023
DOI: 10.1186/s12890-023-02326-6
|View full text |Cite
|
Sign up to set email alerts
|

Identification of biomarkers related to copper metabolism in patients with pulmonary arterial hypertension

Abstract: Background The pathogenesis of pulmonary arterial hypertension (PAH) and associated biomarkers remain to be studied. Copper metabolism is an emerging metabolic research direction in many diseases, but its role in PAH is still unclear. Methods PAH-related datasets were downloaded from the Gene Expression Omnibus database, and 2067 copper metabolism-related genes (CMGs) were obtained from the GeneCards database. Differential expression analysis and t… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
1
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

citations
Cited by 5 publications
(1 citation statement)
references
References 57 publications
0
1
0
Order By: Relevance
“…PH can be caused by a variety of underlying conditions, such as lung disease, heart disease, or genetic factors [1][2][3]. One specific subtype of PH is called pulmonary hypertension due to hypoxia, which is characterised by increased resistance in the small arteries of the lungs [4][5][6]. HPH is caused by chronic exposure to low oxygen levels, which leads to the narrowing of the pulmonary arteries and an increase in pulmonary vascular Zhidan Hua and Mingming Han are contributed equally to this work.…”
mentioning
confidence: 99%
“…PH can be caused by a variety of underlying conditions, such as lung disease, heart disease, or genetic factors [1][2][3]. One specific subtype of PH is called pulmonary hypertension due to hypoxia, which is characterised by increased resistance in the small arteries of the lungs [4][5][6]. HPH is caused by chronic exposure to low oxygen levels, which leads to the narrowing of the pulmonary arteries and an increase in pulmonary vascular Zhidan Hua and Mingming Han are contributed equally to this work.…”
mentioning
confidence: 99%