Melt conditioning treatment via high shearing on Mg-9Al-1Zn melt was employed to disperse the oxide inclusions, and to harness the well-dispersed particles as the effective heterogeneous nucleation sites for primary α-Mg grains during solidification in high pressure die casting. To reveal the mechanism of property improvement, Prefil pressure filtration cleanliness analyser, field-emission scanning electron microscopy with energy dispersive X-ray spectroscopy and high-resolution transmission electron microscopy were employed in present study. The experimental results showed that the application of high shearing not only improved elongation, ultimate tensile strength and yield strength simultaneously, but also reduced the variation of the mechanical properties of Mg-9Al-1Zn alloy. The improvement was ascribed to the refinement of the primary α-Mg grains formed in both shot sleeve and die cavity, and to the reduction of porosity as well as refinement of Mg17Al12 phases.