Identification of new oxospiro chromane quinoline-carboxylate antimalarials that arrest parasite growth at ring stage

Design, synthesis, and biological evaluation of morpholinopyrimidine derivatives as anti-inflammatory agents

“…The library of bioactive compounds shown a wide range of applications in the field of medicinal chemistry. 16–19 According to the FDA (Food and Drug Administration) database, nitrogen-based heterocyclic compounds are present in over 60% of small molecule drugs, supporting the significance of nitrogen-based heterocycles. 20 The studies signify that benzhydrylpiperazine scaffolds are important scaffolds found in various bioactive compounds with antihistaminic, 21 anti-leishmanial, 22 antibacterial, 23 and anticancer, 24 antimicrobial 25 and anti-inflammatory activity.…”