Identification of novel canine rabies virus clades in the Middle East and North Africa

David, Dan; Hughes, G.; Yakobson, B.; Davidson, Irit; Ün, Hikmet; Aylan, O.; Kuzmin, Ivan V.; Rupprecht, Charles E.

doi:10.1099/vir.0.82352-0

Cited by 59 publications

(67 citation statements)

References 39 publications

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“…The concept of dog-related lineages spilling into wildlife species with further host shifts was consistent for all phylogentic groups shown as part of CosC (I to VI) (8,10,(21)(22)(23)(24)(31)(32)(33)(34). This tendency was also consistent for other groups outside the CosC, such as group IX (35,36).…”

Section: Discussionsupporting

confidence: 65%

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Enzootic Rabies Elimination from Dogs and Reemergence in Wild Terrestrial Carnivores, United States

Velasco-Villa¹,

Reeder²,

Orciari³

et al. 2008

Emerg. Infect. Dis.

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135

146

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To provide molecular and virologic evidence that domestic dog rabies is no longer enzootic to the United States and to identify putative relatives of dog-related rabies viruses (RVs) circulating in other carnivores, we studied RVs associated with recent and historic dog rabies enzootics worldwide. Molecular, phylogenetic, and epizootiologic evidence shows that domestic dog rabies is no longer enzootic to the United States. Nonetheless, our data suggest that independent rabies enzootics are now established in wild terrestrial carnivores (skunks in California and northcentral United States, gray foxes in Texas and Arizona, and mongooses in Puerto Rico), as a consequence of different spillover events from long-term rabies enzootics associated with dogs. These preliminary results highlight the key role of dog RVs and human-dog demographics as operative factors for host shifts and disease reemergence into other important carnivore populations and highlight the need for the elimination of dog-related RVs worldwide.

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Section: Discussionsupporting

confidence: 65%

“…(11,12,(20)(21)(22)(23)(24). Vaccine strains with known American origin were included as surrogates of enzootic dog RVs in the United States.…”

Section: Virusesmentioning

confidence: 99%

Enzootic Rabies Elimination from Dogs and Reemergence in Wild Terrestrial Carnivores, United States

Velasco-Villa¹,

Reeder²,

Orciari³

et al. 2008

Emerg. Infect. Dis.

Self Cite

135

146

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show abstract

“…Indeed, phylogenetically these groups are closely related, and their separation could have occurred about 100 years ago. Given the previous estimation that Asian (dog) RABV variants appear at the root of a time-scaled tree [29], Arctic RABV variants probably evolved via a northerly spread, as recently proposed [19]. Furthermore, Arctic-like viruses appear to have compartmentalized earlier than Arctic viruses.…”

Section: Discussionmentioning

confidence: 87%

“…: AF033905, U22474-6, U22480, U42605-7, U42700-2, U42704, U42706, U42707, U43432-4) ; and (3) the Arctic/Arctic-like and European red fox datasets combined with the addition of 11 further isolates from the same lineage [29] (GenBank accession nos. : DQ837383, DQ837385, DQ837446, DQ837448, DQ837463, U22481, U22482, U22484, U22627, U22629, U22852).…”

Section: Estimation Of the Evolutionary Rate And Application Of A Relunclassified

Arctic and Arctic-like rabies viruses: distribution, phylogeny and evolutionary history

et al. 2007

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Forty-one newly sequenced isolates of Arctic and Arctic-like rabies viruses, were genetically compared to each other and to those available from GenBank. Four phylogenetic lineages of Arctic viruses were identified. Arctic-1 viruses circulate in Ontario, Arctic-2 viruses circulate in Siberia and Alaska, Arctic-3 viruses circulate circumpolarly, and a newly described lineage Arctic-4 circulates locally in Alaska. The oldest available isolates from Siberia (between 1950 and 1960) belong to the Arctic-2 and Arctic-3 lineages and share 98.6-99.2% N gene identity with contemporary viruses. Two lineages of Arctic-like viruses were identified in southern Asia and the Middle East (Arctic-like-1) and eastern Asia (Arctic-like-2). A time-scaled tree demonstrates that the time of the most recent common ancestor (TMRCA) of Arctic and Arctic-like viruses is dated between 1255 and 1786. Evolution of the Arctic viruses has occurred through a northerly spread. The Arctic-like-2 lineage diverged first, whereas Arctic viruses share a TMRCA with Arctic-like-1 viruses.

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“…Rabies is a serious enzootic disease throughout the Middle East, notably in Jordan, the Syrian Arab Republic, Lebanon and the Islamic Republic of Iran (5). In Asia, 8 countries have been reported as rabies-free: Japan, Malaysia, Hong Kong, Singapore, Taiwan, Qatar, Bahrain and the United Arab Emirates (UAE) (6).…”

Section: Introductionmentioning

confidence: 99%

Epidemiology of rabies in Oman: a retrospective study (1991–2013)

et al. 2015

Easter Mediterr Health J

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Animal bites and rabies are under-reported in many developing countries and there is poor understanding of the disease burden. The aim of this study was to map the epidemiology of animal bites and rabies in Oman over the period 1991-2013. In a cross-sectional, descriptive, surveillance-based study, all data about animal bites and rabies from the national communicable disease surveillance system were analysed. A total of 22 788 cases of animal bites were reported. Most bites were to males (70%) and the 10-19 year age group (26%). Cats were the most common animal and upper extremities were the most common bite site. There were 8 rabies cases reported during the study period, mostly due to bites from wild animals, with 100% mortality. Of 758 suspected animals tested, 56.1% were positive for rabies; foxes had the highest positivity rate (70.1%). The high incidence of animal bites in Oman emphasizes the importance of a rabies prevention and control programme. . L'animal mordeur le plus fréquent était le chat et les membres supérieurs représenteraient le site le plus souvent mordu. Pendant la période de l'étude, huit cas de rage ont été rapportés, essentiellement dus à des morsures par des animaux sauvages, avec un taux de mortalité de 100 %. Sur les 758 animaux suspects dépistés, 56,1 % étaient positifs pour la rage ; les renards avaient le pourcentage positif le plus élevé (70,1 %). Cette forte incidence des morsures animales à Oman souligne l'importance d'un programme de prévention et de lutte concernant la rage.

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Identification of novel canine rabies virus clades in the Middle East and North Africa

Cited by 59 publications

References 39 publications

Enzootic Rabies Elimination from Dogs and Reemergence in Wild Terrestrial Carnivores, United States

Enzootic Rabies Elimination from Dogs and Reemergence in Wild Terrestrial Carnivores, United States

Arctic and Arctic-like rabies viruses: distribution, phylogeny and evolutionary history

Epidemiology of rabies in Oman: a retrospective study (1991–2013)

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