Identification of phenolics in the fruit of emblica (Phyllanthus emblica L.) and their antioxidant activities

Liu, Xiaoli; Cui, Chun; Zhao, Ming; Wang, Jinshui; Luo, Wei; Yang, Bao; Jiang, Yueming

doi:10.1016/j.foodchem.2008.01.071

Cited by 195 publications

(120 citation statements)

References 32 publications

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“…All these results are related to the presence of antioxidant compounds present in the extract (Table I), as the groups of polyphenols and flavonoids. This information confirms the data from the literature that phenolic compounds, especially flavonoids act in the oxidative metabolism, not by changing the enzymatic defenses, but by directing neutralizing of reactive species in order to stabilize them (Liu et al, 2008).…”

Section: Resultssupporting

confidence: 90%

Evaluation of basil extract ( Ocimum basilicum L.) on oxidative, anti-genotoxic and anti-inflammatory effects in human leukocytes cell cultures exposed to challenging agents

Güez

Souza

Fischer

et al. 2017

Braz. J. Pharm. Sci.

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Ocimum is one of the most important genera of the Lamiaceae family. Several studies about basil and its popular use reveal many characteristics of the herb, including its use as antioxidant, anti-aging, antiinflammatory, anti-carcinogenic, anti-microbial, and cardiovascular agents, among others. In this paper, we evaluated genotoxic, oxidative, and anti-inflammatory parameters from the extract of Ocimum basilicum in different concentrations, using human leukocytes cultures exposed to challenging agents. Our results confirm that the O. basilicum extract acts as an antioxidant and effectively reverts or subjugates the effects of high oxidizing agents such as hydrogen peroxide. These actions are attributed to its composition, which is rich in polyphenols and flavonoids as well as compounds such as rosmarinic acid, all of which have well-known antioxidant activity. We also show that our basil extract presents anti-inflammatory properties, the mechanism of which is a composed interaction between the inhibition of pro-inflammatory mediator and the stimulation of anti-inflammatory cytokines. Although pharmacodynamics studies are necessary to evaluate the activities in vivo, our results demonstrated that basil could act as an antioxidant and anti-inflammatory and a possible alternative for medicinal treatment. Uniterms:Ocimum basilicum/evaluation. Ocimum basilicum/genotoxic effects. Ocimum basilicum/ anti-inflammatory properties. Medicinal plants/study.

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Section: Resultssupporting

confidence: 90%

Evaluation of basil extract ( Ocimum basilicum L.) on oxidative, anti-genotoxic and anti-inflammatory effects in human leukocytes cell cultures exposed to challenging agents

Güez

Souza

Fischer

et al. 2017

Braz. J. Pharm. Sci.

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“…Phyllanthus emblica L. (PE) or Thai-Makham Pom is a famous plant recently used as traditional medicine for many properties. All part extracts of PE have been reported to have high phenolic contents and antioxidant capacities (Iamsaard et al, 2014a(Iamsaard et al, , 2014bLiu et al, 2008;el-Mekkawy et al, 1995;Khanna & Bansal, 1975;Srivastava & Ranjan, 1967;Theresa et al, 1965;Basa & Srinivasuku, 1987). PE extract has been reported to have capacity in lipid peroxidation inhibition and anti-cancers (Krishnami & Mirunalini, 20012;Lou et al, 2011;Zhong et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Phyllanthus emblica L. Branch Extract Ameliorates Testicular Damage in Valproic Acid-Induced Rats

et al. 2015

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SUMMARY:Valproic acid (VPA), widely used in treating epileptic patients, can damage reproductive parameters causing male infertility. This study aimed to investigate protective effect of Phyllanthus emblica L. branch (PE) extract on rat testicular damage induced with VPA. Male rats were divided into 6 groups (control, VPA, 250 mg/kgBW PE only, and 50, 100, 250 mg/kgBW PE+VPA, respectively). Animals were pretreated with PE for 23 days and co-administered with VPA for 10 days before all reproductive parameters were determined. The results showed all doses of PE significantly protected the decrease testicular weight and testosterone level in VPA rats. PE significantly improved the decrease sperm concentration in VPA treated rats. Moreover, testicular histology of PE+VPA groups showed declining of testicular histopathologies as compared to VPA group. Therefore, it seems that PE branch extract can prevent testicular damages including male reproductive parameters in rats induced with VPA.

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“…emblica (Indian gooseberry) fruit extract contained a high amount of phenolic compounds (290 mg/g extract) and ascorbic acid (11.21%) [23] . Liu et al [31] . reported that Indian gooseberry extract contained geraniin, quercetin 3-β-Dglucopyranoside, kaempferol 3-β-D-glucopyranoside, isocorilagin, quercetin and kaempferol.…”

Section: Total Phenolic and Flavonoid Contentsmentioning

confidence: 99%

Antimicrobial activity of Thai medicinal plants against beverage spoilage microorganisms and their potential in retarding Alzheimer’s disease progression

Nanasombat¹,

Bubpasawan²,

Tamaput³

et al. 2014

Phcog Commn.

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Thai medicinal plants (34 crude methanolic extracts) were tested for their antimicrobial activities, antiacetylcholinesterase and antioxidant activities, total phenolic and flavonoid contents. Acorus calamus, Cassia alata, Crocus sativus, Nymphaea lotus and Phyllanthus emblica extracts showed strong antimicrobial activity against spoilage yeasts, lactic acid bacteria and acetic acid bacteria tested. Most susceptible yeast strains were Rhodotorula glutinis and Schizosaccharomyces pombe. Kaempferia parviflora, Nelumbo nucifera, Rauvolfia serpentina and Centella asiatica extracts exhibited strong acetylcholinesterase inhibitory activity (more than 70 % inhibition). Terminalia chebula, Cinnamomum bejolghota, Uncaria gambir and P. emblica extracts had the strongest antioxidant activity, EC 50 of 387.23 -490.47 µg extract/mg 2, 2-diphenyl-1-picrylhydrazyl (DPPH) by DPPH radical scavenging activity method and reducing capacity of 656.19 -774.41 mmol Fe(II)/g by ferric reducing antioxidant power (FRAP) method. U. gambir extract had the highest total phenolic and flavonoid contents (771.59 mg gallic acid equivalents (GAE)/g and 2,292.43 mg quercetin equivalents (QE)/g, respectively).

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Identification of phenolics in the fruit of emblica (Phyllanthus emblica L.) and their antioxidant activities

Cited by 195 publications

References 32 publications

Evaluation of basil extract ( Ocimum basilicum L.) on oxidative, anti-genotoxic and anti-inflammatory effects in human leukocytes cell cultures exposed to challenging agents

Evaluation of basil extract ( Ocimum basilicum L.) on oxidative, anti-genotoxic and anti-inflammatory effects in human leukocytes cell cultures exposed to challenging agents

Phyllanthus emblica L. Branch Extract Ameliorates Testicular Damage in Valproic Acid-Induced Rats

Antimicrobial activity of Thai medicinal plants against beverage spoilage microorganisms and their potential in retarding Alzheimer’s disease progression

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