Identification of proteins in housefly (Musca domestica) larvae powder by LC-MS/MS and their potential medical relevance

Abstract

Housefly larvae (HL) powder was used to cure wounds centuries ago for its good nutritional and pharmacological values.

Identification of Putative Cell‐entry‐inhibitory Peptides against SARS‐CoV‐2 from Edible Insects: An in silico Study

“…Figure 1 shows a flowchart of the study. A total of 24 major proteins found in three edible insects, namely mealworms, housefly larvae and silkworm cocoons [14][15][16], were studied. Sequences of the proteins were downloaded from the UniProt web server (http://www.…”

“…In this study, the mealworm, silkworm cocoon and housefly larvae were investigated. The three insect samples were chosen because previous studies [14][15][16] have highlighted their nutritional and medicinal values. The aim of this study was to identify potential SARS-CoV-2 cell entry inhibitors from edible insects through in silico analysis, focusing on high GI-absorption peptides that could bind to the RBD of the SARS-CoV-2 spike proteins.…”

Applications of tandem mass spectrometry (MS/MS) in antimicrobial peptides field: Current state and new applications

“…Animal mucus secretions are ground in a blender with an extraction buffer [ 66 ]. The extraction process may include additional steps, such as heating [ 67 ], removal of excess protein, prefractionation [ 68 ], or removal of tannins [ 69 ], or degreasing [ 70 ], if necessary for large protein peptides or small molecules with higher content. Protein and peptides can be extracted using simple solvent extraction techniques [ 71 ].…”