Identification of SNPs in MYOD gene family and their associations with carcass traits in cattle

Bhuiyan, M. S. A.; Kim, N.K.; Cho, Y.M.; Yoon, Duhak; Kim, K.S.; Jeon, Jin-Tae; Lee, Jun Heon

doi:10.1016/j.livsci.2009.05.019

Cited by 49 publications

(37 citation statements)

References 30 publications

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“…Our results showed that the Myf6-ApaLI locus was significantly related to CL, and individuals of the BB genotype had significantly longer CLs compared to those of AA and AB genotypes (P < 0.05). This result is in contrast to the g.183T>C polymorphism in Hanwoo that did not show any significant associations with growth and carcass traits evaluated (Bhuiyan et al, 2009 Results from this study indicate that MyoD1 and Myf6 have potential effects on carcass and meat quality traits, opening up possibilities for improvements in cattle breeding and geneassisted selection. In conclusion, this preliminary study on polymorphisms of the MyoD1-BglI and Myf6-ApaLI loci in cattle revealed that these two SNPs might be useful genetic markers.…”

Section: Discussioncontrasting

confidence: 81%

“…Several studies have demonstrated associations between MyoD1 and growth traits. Association analysis between growth traits (LW and CW) and the g.1274A>G locus revealed that heterozygous animals appeared advantageous for LW and CW compared to their homozygous counterparts (Bhuiyan et al, 2009). In addition, the C→T mutation locus at the 3ꞌ untranslated region showed significant associations with heart girth and body weight in yak populations (Chu et al, 2012).…”

Section: Discussionmentioning

confidence: 96%

“…In cattle, several studies have reported associations between the two genes with growth traits in different breeds (Bhuiyan et al, 2009;Wang et al, 2011;Chu et al, 2012). Yet, few studies have described the relationship between the SNPs of these two genes and carcass and meat quality traits in cattle.…”

Section: Introductionmentioning

confidence: 99%

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Polymorphism of MyoD1 and Myf6 genes and associations with carcass and meat quality traits in beef cattle

Du¹,

Gan²,

Yuan³

et al. 2013

Genet. Mol. Res.

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ABSTRACT. Myogenic determination factor 1 (MyoD1) and myogenic factor 6 (Myf6) genes belong to the myogenic differentiation (MyoD) gene family, which play key roles in growth and muscle development. The study aimed to investigate the effects of variants in cattle MyoD1 and Myf6 on carcass and meat traits. We screened single nucleotide polymorphisms (SNPs) of both genes in 8 cattle populations, including Simmental, Angus, Hereford, Charolais, Limousin, Qinchuan, Luxi, and Jinnan by sequencing. The G782A locus was identified in exon 1 of MyoD1 (MyoD1-BglI) as well as the T186C locus in exon 1 of Myf6 (Myf6-ApaLI). For the two SNPs, the A allele was significantly more frequent than the B allele in the populations tested. The χ 2 test showed that the MyoD1-BglI locus conformed to Hardy-Weinberg equilibrium in the 8 populations, as did the Myf6-ApaLI locus, with the exception of Polymorphism of MyoD1 and Myf6 in beef cattle the Simmental population (P > 0.05). Association analysis revealed that the MyoD1-BglI locus was significantly associated with loin muscle area (LMA) (P < 0.05), and the Myf6-ApaLI locus was significantly associated with carcass length (CL) (P < 0.05). Animals with BB and AB genotypes for the MyoD1-BglI locus had larger LMAs compared to animals with AA genotype. Individuals with BB genotype had longer CLs compared to those with AA and AB genotypes. We conclude that the two SNPs might provide useful genetic markers, opening up new possibilities for cattle breeding and improvements in gene-assisted selection.

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Section: Discussioncontrasting

confidence: 81%

Section: Discussionmentioning

confidence: 96%

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Polymorphism of MyoD1 and Myf6 genes and associations with carcass and meat quality traits in beef cattle

Du¹,

Gan²,

Yuan³

et al. 2013

Genet. Mol. Res.

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“…These results have been further confirmed by SNP studies of the MyoG gene (Kapelanski et al, 2005;Wyszynska-Koko et al, 2006;Verner et al, 2007). Bhuiyan et al (2009) detected a G>C mutation in exon 1 among six breeds, including Hanwoo, Angus, Simmental, Hereford, Shorthorn, Brahman, and Red Chittagong.…”

Section: Discussionmentioning

confidence: 54%

A novel polymorphism of the myogenin gene is associated with body measurement traits in native Chinese breeds

Xue¹,

Zan²,

Gao³

et al. 2011

Genet. Mol. Res.

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ABSTRACT. Using PCR-SSCP and DNA sequencing technology, we examined the association of single nucleotide polymorphisms (SNPs) in the bovine MyoG gene with body measurement traits in 779 individuals of six native Chinese cattle breeds, namely Luxi, Luxi × Simmental crossbred, Nanyang, Xia'nan, Jiaxian red, and Qinchuan. A novel SNP, T314C, was detected. Allelic frequencies of MyoG-T/C in the six breeds were 0.8308/0. 1692, 0.8774/0.1226, 0.8021/0.1979, 0.8209/0.1791, 0.8630/0.1370, 0.8044/0.1956, respectively. Least squares analysis revealed a significant (P < 0.05) association of the MyoG SNP with rump length in four breeds (Luxi, Xia'nan, Jiaxian red, and Qinchuan), with hucklebone width in three breeds (Luxi × Simmental crossbred, Nanyang and Xia'nan), with waist height in two breeds (Luxi × Simmental crossbred and Nanyang) and with body length in the Luxi breed. We conclude that the MyoG SNP has potential as a genetic marker for economically relevant body measurement traits in native Chinese cattle breeds.

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“…Furthermore, Polymorphism in MyoD gene family and their effects on growth and carcass traits in Korean cattle, Han Woo, has also been reported [13]. Yet, to our best knowledge, very little research has reported on the relationship between the polymorphism of MyoD1 gene and meat quality traits in cattle.…”

Section: Introductionmentioning

confidence: 99%

Identification of the SNPs in MyoD Gene and Their Associations in Pakistani Indegeneous Cattle’s

Ujan¹,

Shaikh²,

Jatoi³

et al. 2014

IJBBB

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Identification of SNPs in MYOD gene family and their associations with carcass traits in cattle

Cited by 49 publications

References 30 publications

Polymorphism of MyoD1 and Myf6 genes and associations with carcass and meat quality traits in beef cattle

Polymorphism of MyoD1 and Myf6 genes and associations with carcass and meat quality traits in beef cattle

A novel polymorphism of the myogenin gene is associated with body measurement traits in native Chinese breeds

Identification of the SNPs in MyoD Gene and Their Associations in Pakistani Indegeneous Cattle’s

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