“…Samples from patients with a poorer prognosis tended to engraft better (Ailles et al, 1999;Rombouts et al, 2000b;Yan et al, 2009). Adverse prognostic features, such as high WBC, FLT3-ITD positive, high CD34 expression, relapse (Giavazzi et al, 1995;Rombouts et al, 2000b;Lumkul et al, 2002;Sanchez et al, 2009), were also associated with an enhanced engraftment potential in AML model. However, high WBC, relapse and FLT3-ITD were not predictors of engraftment success in other studies (Ailles et al, 1999;Pearce et al, 2006).…”