Identification of waist circumference cutoffs for abdominal obesity in the Chinese population: a 7.8-year follow-up study in the Shanghai urban area

Abstract

Aim: To identify the appropriate visceral adipose tissue (VAT) cutoff values for the diagnosis of abdominal obesity in predicting diabetes and the corresponding waist circumference in the Chinese population. Methods: At baseline, 381 volunteers aged 35-75 years were enrolled without diabetes from the Shanghai urban area. Anthropometry and VAT area determined by magnetic resonance imaging were measured. During the average 7.8 years of follow-up, glucose tolerance was monitored. Receiver operating characteristic (ROC) curve analysis was used to define the optimal cutoff points for abdominal obesity. Results: At the end of the study, 290 participants were followed up, in which 63 participants developed diabetes. Using ROC curve analyses in participants with normal glucose regulation, the appropriate VAT cutoff was 90 cm 2 for both genders to predict diabetes development. In logistic regression models, the relative risks (95% confidence intervals) of VAT value over 90 cm 2 were 3.35 (1.10-10.18, P ¼ 0.033) in men and 4.57 (1.73-12.07, P ¼ 0.002) in women after adjusted for age, impaired glucose regulation, hypertension and dyslipidemia. The optimal waist circumference cutoffs were 88 cm for men and 82 cm for women to indicate VAT value over 90 cm 2 in ROC analyses. Conclusion: VAT cutoff of 90 cm 2 is useful for defining visceral obesity in Chinese individuals. The appropriate waist circumference cutoffs for abdominal obesity are 88 cm for men and 82 cm for women in the Chinese population.

Insulin Pump Therapy – Influence on Body Fat Redistribution, Skeletal Muscle Mass and Ghrelin, Leptin Changes in T1D Patients

“…Women in our group had higher TBF, as shown by greater thickness of subcutaneous fat and higher visceral fat mass, when compared to males. Higher visceral fat tissues in females with DM has also been reported by Ye et al [4]. Higher VFA in women with T1D could be related to more frequent oscillations in glycaemia during the menstrual cycle.…”

“…In non-obese women with T1D, the higher central depots of fats are the main determinant of MS, while peripheral fat distribution and total fat percentage show no correlation with MS [1]. Men without diabetes have higher visceral adiposity compared to women without diabetes, while men with diabetes have lower visceral adiposity compared to women with diabetes [4]. Results of The Diabetes Control and Complications Trial Research Group (DCCT) showed that intensive glycaemic control reduces the incidence and progression of microvascular complications in T1D [5], but also leads to body weight (BW) increase [6].…”

Clinical utility of visceral adipose tissue for the identification of cardiometabolic risk in white and African American adults

“…Several studies have identified thresholds of VAT that are related to elevated cardiometabolic risk factors and metabolic syndrome (MetS) in white men and women (5)(6)(7)(8)(9). Limited studies have also identified optimal thresholds of VAT in other ethnic groups such as Indians (10), Chinese (11), Koreans (12,13), Japanese (14,15), and Japanese Americans (16).…”

Asexuality Development among Middle Aged and Older Men

“…Body mass index (BMI) was calculated as measured weight in kilograms divided by measured height in meters squared and categorized using the World Health Organization (WHO) classifications [6]: overweight (≥25 kg/m 2 ) or not (<25 kg/m 2 ). Waist circumference (WC) measurements were used as a measure of central adiposity, and classified into two categories: obesity (≥90 cm) or not (<90 cm)) [7].…”