1997
DOI: 10.1002/(sici)1096-9098(199705)65:1<34::aid-jso7>3.3.co;2-1
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Identification of women with T1‐T2 breast cancer at low risk of positive axillary nodes

Abstract: Background and Objectives:The diagnostic and therapeutic significance of axillary dissection has been questioned. We sought to define a subgroup of patients with early-stage breast cancer who are at low risk for positive axillary nodes. Methods: Between 1970 and 1995, 1,598 women with stage I and II breast cancer underwent level I-II axillary dissection with a minimum of 10 nodes removed. The following factors were examined in univariate analysis for predicting positive nodes: race, method of detection, locati… Show more

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Cited by 22 publications
(32 citation statements)
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“…Lymphovascular invasion proved to be the strongest independent predictor of nodal involvement in two series, 13,18 underscoring the significance of this tumour characteristic 16,20 . This finding was confirmed in the present study.…”
Section: Discussionsupporting
confidence: 88%
“…Lymphovascular invasion proved to be the strongest independent predictor of nodal involvement in two series, 13,18 underscoring the significance of this tumour characteristic 16,20 . This finding was confirmed in the present study.…”
Section: Discussionsupporting
confidence: 88%
“…A common route of spread for breast carcinoma is first through the axillary lymph nodes, and the incidence of ALNM increases with larger tumors (11)(12)(13)(14). Table 5 demonstrates the strong relationship between the primary tumor size and ALNM.…”
Section: Discussionmentioning
confidence: 98%
“…Increased age and a high BMI have been linked to poor prognosis and more invasive cancer types (9–11). However, increased age has recently been associated with a decreased spread of malignancies to the axillary lymph nodes (12,13). Additionally, age may be related to an increased incidence of mapping failure, making the mapping of senior adults controversial.…”
Section: Discussionmentioning
confidence: 99%