Identifikasi Dan Penetapan Kadar Sildenafil Sitrat Pada Jamu Kuat Lelaki Yang Beredar Di Kota Makassar

Waris, Risda; Kadir, Abd; Akbar, Chairil

doi:10.33096/jifa.v5i1.74

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Inhibitor PDE-5 works by increasing the levels of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum indirectly by inhibition of the enzyme PDE-5 by increasing nitrogen oxide (NO). This leads to the effect of smooth muscle relaxation and an increased inflow of blood in the corpus cavernosum 43 . Side effects of consumption of herbs containing Sildenafil are irregular heartbeat, shortness of breath, angina, myocardial infarction, stroke, priapism, sudden hearing loss, and blindness 44 .…”

Section: Resultsmentioning

confidence: 99%

Analysis of Medicinal Chemicals Contained on Jamu: A Review

Syahfitr¹,

Asra²

2021

Asian J Pharm Res Dev

View full text Add to dashboard Cite

Background: Jamu is commonly known as an Indonesian traditional herbal medicine that contains ingredients or ingredients derived from plants, animals, minerals, galenic, or mixtures of these ingredients that have been hereditary for medicinal use. Some studies reported the presence of medicinal chemicals that are deliberately added to Jamu. Jamuthat containing medicinal chemicals usually had a faster healing effect compared to Jamu that do not contain medicinal chemicals. Jamu added medicinal chemicals cause serious side effects if it is consumed regularly, overdose, and long period consumption with uncontrolled dosage or its interaction with other substances on jamu formulation. Purpose: This review article aims to summarize several methods used to analyze medicinal chemicals contained in jamu. Data source:The author created thisreview article by conducting literature studies. The literature was collected from national and international journals published in the last ten years (2010-2020). The works of literature were collected from trusted online journal sites such as the digital library, Google, Google scholar/Google Cendekia, PubMed, ScienceDirect, NCBI, Researchgate, and other E-resource with the keyword “Jamu”, “medicinal chemicals”, and “analysis of medicinal chemicals”. Conclusion: Jamu products that containing medicinal chemicals are jamu pegal linu, weight loss, stamina enhancer, diabetes, antihypertensive and dietary supplements. The medicinal chemicals used are sodium diclofenac, paracetamol, piroxicam, ibuprofen, dexamethasone, mefenamic acid, phenolphthalein, sibutramine, fenfluramine, sildenafil, tadalafil, thiosildenafil, caffeine, ephedrine, nifedipine, glibenclamide. Herbal Medicine was analyzed by the TLC method (thin layer chromatography), Densitometry-chromatography, thin-layer chromatography-Spectrophotometry, SERS-thin layer chromatography, Spectrophotometry, HPLC (High-Performance Liquid Chromatography), HPLC-ESI-MS/MS (high-performance liquid. chromatography/electrospray ionization tandem mass spectrometry), HPLC-Densitometry (High-Performance Liquid Chromatography-densitometry), UHPLC-Q-ORTIP HERMS (ultra-high-performance liquid chromatography-Quadrupole-orbitrap high-resolution mass spectrometry), UPLC/Q-TOF MS (ultra-performance liquid chromatography (UPLC) coupled with quadrupole-time-of-flight mass spectrometry (Q-TOF MS), Capillary electrophoresis (CE), GC-MS (Gas Chromatography-Mass Spectrometry), LC-MS (Liquid Crhomatogaph Mass) Spectrometry), Prototype Test-Strip, Infrared spectroscopy.

show abstract

Section: Resultsmentioning

confidence: 99%

Analysis of Medicinal Chemicals Contained on Jamu: A Review

Syahfitr¹,

Asra²

2021

Asian J Pharm Res Dev

View full text Add to dashboard Cite

show abstract

“…KLT-Densitometri digunakan untuk menentukan identitas dan kadar senyawa dengan cara noda yang terpisah pada plat KLT tersebut dimasukkan kedalam instrument yang kadarnya ditentukan berdasarkan hubungan Area Under Curve (AUC) masing-masing noda pada plat (Sherma, 1994). Dalam menggunakan alat KLT Densitometri yang memiliki kepekaan yang tinggi untuk menganalisis senyawa yang dideteksi maka dalam pengerjaan diperhatikan jumlah dan teknik penotolan ekstrak (Waris et al, 2013).…”

Section: Pembahasanunclassified

ANTIHYPERGLYCHEMIC ACTIVITY TEST OF EXTRACT, METHANOL FRACTION AND N-HEKSAN FRACTION OF KETAPANG LEAF (Terminalia catappa) IN ALLOXAN-INDUCED WHITE RATS

Nurhayati

2023

wiyata

View full text Add to dashboard Cite

Background: Ketapang leaf (Terminalia catappa) can be used as a traditional medicine that has the potential activity to reduce blood glucose levels in the body. Objective: To determine the activity of extracts and fractions of ketapang leaves in reducing blood glucose levels of rats induced by alloxan. Methods: This study was an experimental study using 30 male wistar rats as test animals divided into 6 groups. Group I was healthy control, group II was negative control (K-) that given 0.5% Na CMC solution, group III was positive control (k+) that given metformin suspension, groups IV, V, and VI were given ketapang leaf extract, methanol fraction and n-hexane fraction, respectively. Results: The ethanol extract and methanol fraction of ketapang leaves can reduce blood glucose levels in white rats because they contain flavonoid compounds which are thought to have antihyperglycemic activity. Conclusions: The methanol fraction of ketapang leaves (Terminalia catappa) was most effective in reducing blood glucose levels in alloxan-induced white rats.

show abstract

Identifikasi Dan Penetapan Kadar Sildenafil Sitrat Pada Jamu Kuat Lelaki Yang Beredar Di Kota Makassar

Cited by 2 publications

References 0 publications

Analysis of Medicinal Chemicals Contained on Jamu: A Review

Analysis of Medicinal Chemicals Contained on Jamu: A Review

ANTIHYPERGLYCHEMIC ACTIVITY TEST OF EXTRACT, METHANOL FRACTION AND N-HEKSAN FRACTION OF KETAPANG LEAF (Terminalia catappa) IN ALLOXAN-INDUCED WHITE RATS

Contact Info

Product

Resources

About