Identifikasi Jamur Pada Pasien Penderita Tuberkulosis Paru di RSUP  H. Adam Malik Medan

Setiyawati, Dewi; Situmeaang, Suryani M.Florence

doi:10.34012/jkpi.v3i2.2042

Cited by 2 publications

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“…Resistensi primer ini biasa dijumpai pada penderita Human Immunodeficiency Virus (HIV). Sedangkan resistensi sekunder yaitu resistensi yang didapat selama terapi pada orang yang sebelumnya sensitif terhadap obat (Syahrini, 2008). Pada pasien dengan riwayat pengobatan sebelumnya, kemungkinan terjadi resistensi sebesar 4 kali lipat, sedangkan terjadinya MDR-TB sebesar 10 kali lipat atau lebih dibandingkan dengan pasien yang belum pernah diobati.…”

Section: Pendahuluanunclassified

Faktor-faktor yang berhubungan dengan Multidrug Resistant Tuberculosis (MDR-TB) pada pasien tuberkulosis paru

Saputra,

Yulendasari,

Kusumaningsih

2022

J.HolHealth

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Background: Anti-TB drug resistance is basically a man-made phenomenon as a result of inadequate treatment of TB patients. Based on the data in the Sub-Division of Medical Records, Dr. H. Abdul Moeloek Hospital Lampung Province recorded as many as 62 MDR-TB patients in the period 2022.Purpose: To determine factors associated with Multidrug Resistant Tuberculosis (MDR-TB) among patients with pulmonary tuberculosis (TB)Method: A quantitative with a case control design. The study population was all patients from the MDR Polyclinic, Regional General Hospital Dr. H. Abdul Moeloek Lampung Province in February 2021 a total of 62 people. The sample is 62 cases and 62 controls. The statistical test used is the chi square test with the help of a computer.Results: Showed that, out of 124 respondents, the majority of respondents were in the productive age range of 76 respondents (61.3%), high socioeconomic status of 74 respondents (59.7%), abnormal nutritional status of 82 respondents (66.1%) , adherence to taking medication was low by 68 respondents (54.8%), comorbidities by 79 respondents (63.7%), smoking by 72 respondents (58.1%).Conclusion: There was no relationship between age with MDR TB cases, but there was a relationship between socioeconomic, nutritional status, medication adherence and smoking habits with MDR TB cases and to prevent an increase number of MDR-TB in Lampung Province. Suggestion: By using a predictive index of MDR-TB incidence both at the community level and at the health worker level and the community level it is useful for initial screening for MDR-TB prevention in TB patients.Keywords: Multidrug Resistant Tuberculosis (MDR-TB); Patient; Pulmonary tuberculosisPendahuluan: Resistensi obat anti TB (OAT) pada dasarnya adalah suatu fenomena buatan manusia sebagai akibat dari pengobatan pasien TB yang tidak adekuat. Berdasarkan data di sub-bagian rekam medis RSUD Dr. H. Abdul Moeloek Provinsi Lampung tercatat sebanyak 62 pasien MDR-TB pada periode tahun 2022.Tujuan: Mengetahui faktor-faktor yang berhubungan dengan Multidrug Resistant Tuberculosis (MDR-TB) pada pasien Tuberkulosis paruMetode: Penelitian kuantitatif dengan rancangan case control. Sampel sejumlah 62 orang. Sampel 62 kasus dan 62 kontrol. Uji statistik yang digunakan adalah uji chi square dengan bantuan komputer.Hasil: Dari 124 responden didapatkan hasil bahwa sebagian besar responden dalam rentang usia produktif sebanyak 76 responden (61,3%), sosial ekonomi tinggi sebanyak 74 responden (59,7%), status gizi tidak normal sebanyak 82 responden (66,1%), kepatuhan minum obat rendah sebanyak 68 responden (54,8%), penyakit penyerta sebanyak 79 responden (63,7%), merokok sebanyak 72 responden (58,1%).Simpulan: Menunjukan tidak terdapat hubungan usia dengan kasus TB MDR namun ada hubungan sosial ekonomi, status gizi, kepatuhan minum obat dan kebiasaan merokok dengan kasus TB MDR.Saran: Perlunya melakukan pencegahan terjadinya peningkatan TB-MDR di Provinsi Lampung dengan menggunakan indeks prediktif kejadian TB-MDR baik di tingkat masyarakat maupun petugas kesehatan. Pada tingkat masyarakat berguna untuk untuk skrining awal untuk pencegahan TB-MDR pada penderita TB.

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Section: Pendahuluanunclassified

Faktor-faktor yang berhubungan dengan Multidrug Resistant Tuberculosis (MDR-TB) pada pasien tuberkulosis paru

Saputra,

Yulendasari,

Kusumaningsih

2022

J.HolHealth

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“…Aspergillosis generally only develops in immunocompromised individuals. In immunocompromised patients, inhaled and colonized spores invade the lung tissue and grow until they cause lung tissue damage [8].…”

Section: Introductionmentioning

confidence: 99%

Detection of Aspergillus Sp Fungus in Tuberculosis Patients with A Treatment Length of 2 Months using the Polymerace Chain Reaction (Pcr) Method

Faidha,

Muh. Nasrum Massi,

Irawati Djahruddin

et al. 2023

J. Adv. Zool.

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This study aims to detect the presence or absence of the Aspergillus sp fungus in Tuberculosis Patients within a 2 month treatment period. This research was carried out in the Microbiology Laboratory at Hasanuddin University Teaching Hospital. Laboratory methods. Samples were obtained from the Tabaringan and Pattingaloang Community Health Centers in Makassar City. Then testing was carried out using culture techniques and polymerace chain reaction techniques. The research results showed that by using the culture method from 30 samples, 9 samples obtained growing media, for 2 samples it was suspected that Aspergillus sp fungus was growing. Then for the polymerace chain reaction (PCR) method, from 30 samples the presence of Aspergillus sp fungus was detected, 4 samples using ASAP primers, then carried out again using ASPU primers (ASPU+Af3r, ASPU+Ni1r, ASPU+Fl2r) which resulted in 1 Aspergillus niger sample. From the results of this research, it can be concluded that the factor that causes the growth of fungus is the long-term administration of anti-tuberculosis drugs which only suppress bacteria from pulmonary tuberculosis.

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Identifikasi Jamur Pada Pasien Penderita Tuberkulosis Paru di RSUP H. Adam Malik Medan

Cited by 2 publications

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Faktor-faktor yang berhubungan dengan Multidrug Resistant Tuberculosis (MDR-TB) pada pasien tuberkulosis paru

Faktor-faktor yang berhubungan dengan Multidrug Resistant Tuberculosis (MDR-TB) pada pasien tuberkulosis paru

Detection of Aspergillus Sp Fungus in Tuberculosis Patients with A Treatment Length of 2 Months using the Polymerace Chain Reaction (Pcr) Method

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