Identifying the Association Among Risk Factors and Mortality in Trauma Patients With Intra-Abdominal Hypertension and Abdominal Compartment Syndrome

Harrell, Bradley R.; Melander, Sheila

doi:10.1097/jtn.0b013e318261d2f1

Cited by 4 publications

(2 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The findings of this study are significant for several reasons; this study adds to the limited number of studies that have examined how certain clinical and laboratory markers correlate with specific outcomes observed in trauma patients diagnosed with ACS. [ 10 11 12 ] In addition, previous research on ACS consisted largely of single-institutional reviews, which may restrict the general applicability of their findings. This study drew data from three urban Level I Trauma centers, which may provide for findings that are more generalizable.…”

Section: Discussionmentioning

confidence: 99%

“…[ 10 11 ] Each ACS sub-type likely has its own unique pathophysiology and set of markers, necessitating a different diagnostic and therapeutic approach in each type. [ 12 13 14 ] In addition, some markers may be associated with the development of particular ACS complications, but these relationships have not been well-established. The purpose of this study is to identify the strength of association between different clinical and laboratory variables and the occurrence of specific adverse outcomes in trauma patients diagnosed with ACS.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Abdominal compartment syndrome in trauma patients: New insights for predicting outcomes

Shaheen

Crandall

Nicolson

et al. 2016

J Emerg Trauma Shock

View full text Add to dashboard Cite

Context:Abdominal compartment syndrome (ACS) is associated with high morbidity and mortality among trauma patients. Several clinical and laboratory findings have been suggested as markers for ACS, and these may point to different types of ACS and complications.Aims:This study aims to identify the strength of association of clinical and laboratory variables with specific adverse outcomes in trauma patients with ACS.Settings and Design:A 5-year retrospective chart review was conducted at three Level I Trauma Centers in the City of Chicago, IL, USA.Subjects and Methods:A complete set of demographic, pre-, intra- and post-operative variables were collected from 28 patient charts.Statistical Analysis:Pearson's correlation coefficient was used to determine the strength of association between 29 studied variables and eight end outcomes.Results:Thirty-day mortality was associated strongly with the finding of an initial intra-abdominal pressure >20 mmHg and moderately with blunt injury mechanism. A lactic acid >5 mmol/L on admission was moderately associated with increased blood transfusion requirements and with acute renal failure during the hospitalization. Developing ACS within 48 h of admission was moderately associated with increased length of stay in the Intensive Care Unit (ICU), more ventilator days, and longer hospital stay. Initial operative intervention lasting more than 2 h was moderately associated with risk of developing multi-organ failure. Hemoglobin level <10 g/dL on admission, ongoing mechanical ventilation, and ICU stay >7 days were moderately associated with a disposition to long-term support facility.Conclusions:Clinical and lab variables can predict specific adverse outcomes in trauma patients with ACS. These findings may be used to guide patient management, improve resource utilization, and build capacity within trauma centers.

show abstract

Section: Discussionmentioning

confidence: 99%