Misconception about stoichiometry and its impact on the chemical equilibrium concept were studied on 245 second-grade students at SMA Negeri 2 Gowa, South Sulawesi, Indonesia. Research instruments were Stoichiometry misconception test (SMT) and chemical equilibrium misconception three tier tests (CEMTT). Semi structured interview was conducted after the administration of the test for fifteen students. SMT consisted of ten items with high validity of 90.70% and reliability coefficient, calculated using Cronbach's alpha, of 0.73 (high). CEMTT consisted of thirdteen items with very high validity of 96.70% and reliability coefficient, calculated using Cronbach's alpha, of 0.95 (very high). The effect of stoichiometry misconceptions on chemical equilibrium was sufficient with limited predictions (r = 0.36). We identified three misconceptions stoichiometry that had impact on the misconceptions of chemical equilibrium concept namely: 1) The number of moles of substances that react is proportional to the number of atoms, relates to the increasing pressure will shift the equilibrium of the gas toward a substance that has more number of atoms; 2) The increasing of concentration will greather surface area, so as to giving rises to a greather number of effective collisions. This is related to the misconception that changes in the amount of solid phase at heterogeneous equilibrium which would shift the equilibrium system; 3) In exothermic reaction there is an increase in reaction enthalpy, relates to the misconception that the increase of temperature in exothermic gas equilibrium will shift towards the product. It was proven that there was a misconception relationship between the stoichiometry and chemical equilibrium, so it is recommended to implement a learning strategy that can prevent students' misconceptions on the concept of chemical equilibrium by eliminating students' misconceptions on the stoichiometry in chemistry learning.