DESCRIPTIONA 70-year-old man presented with non-specifi c chest pains. A low-grade tubulovillous adenoma had previously been removed from his colon and he was an ex-smoker. A chest radiograph revealed multiple pulmonary masses. He subsequently underwent a staging CT examination (fi gure 1a,b) which revealed multiple irregular, predominantly pleurally based masses with foci of calcifi cation, necrosis and cavitation. They measured up to 5.5 cm in diameter. Radiologically they were concerning for malignancy and a CT guided biopsy was performed. The biopsies contained abundant amorphous eosonophilic material which stained with Congo Red, in keeping with amyloid (fi gure 2a,b).