Idiopathic Organ Transplant Chorioretinopathy after Liver Transplantation

Abalem, Maria Fernanda; Carricondo, Pedro Carlos; Pimentel, Sérgio Luís Gianotti; Takahashi, Walter Yukihiko

doi:10.1155/2015/964603

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…While the pathogenesis of CSC is still poorly understood, several risk factors seem to be involved such as younger age, male gender, type-A behavioral pattern, history of organ transplant, pregnancy, systemic blood hypertension, use of exogenous corticosteroids, and endogenous hypercortisolism (5–7). …”

Section: Introductionmentioning

confidence: 99%

Choroidal and Retinal Abnormalities by Optical Coherence Tomography in Endogenous Cushing’s Syndrome

et al. 2016

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ContextCortisol has been suggested as a risk factor for choroidal thickening, which may lead to retinal changes.ObjectiveTo compare choroidal thickness measurements using optical coherence tomography (OCT) in patients with endogenous active Cushing’s syndrome (CS) and to evaluate the occurrence of retinal abnormalities in the same group of patients.DesignCross-sectional study.SettingOutpatient clinic.PatientsEleven female patients with CS in hypercortisolism state as determined by the presence of at least two abnormal measurements from urinary cortisol 24 h, no suppression of cortisol with low dose dexamethasone suppression test, and nocturnal salivary cortisol levels and 12 healthy controls.MethodsChoroidal and retinal morphology was assessed using OCT.Main outcome measuresChoroidal thickness measurements and the presence of retinal changes.ResultsThe mean subfoveal choroidal thickness was 372.96 ± 73.14 µm in the patients with CS and 255.63 ± 50.70 µm in the control group (p < 0.001). One patient (9.09%) presented with central serous chorioretinopathy and one patient (9.09%) with pachychoroid pigment epitheliopathy.ConclusionChoroidal thickness is increased in the eyes of patients with active CS compared to healthy and matched control. Also, 18.18% of patients presented with macular changes, possibly secondary to choroidal thickening. While further studies are necessary to confirm our findings, excess corticosteroid levels seem to have a significant effect on the choroid and might be associated with secondary retinal diseases.

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Section: Introductionmentioning

confidence: 99%

Choroidal and Retinal Abnormalities by Optical Coherence Tomography in Endogenous Cushing’s Syndrome

et al. 2016

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Giraffe or leopard spot chorioretinopathy as an outstanding finding: case report and literature review

Bonyadi

Ownagh

Rahimy³

et al. 2018

Int Ophthalmol

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Leopard spot retinopathy is an uncommon but clinically distinct manifestation of various disorders. BDUMP may present with leopard spot retinopathy, anterior uveal tract involvement and neovascular glaucoma. As EDI-OCT showed involvement and increased thickening of choroid in both cases of BDUMP and IUES, it may be better to consider such cases as leopard chorioretinopathy and categorize these entities as a member of pachychoroid pigment retinopathy disorders.

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Letter to the Editor: Characterization of Choriocapillaris and Choroidal Abnormalities in Alport Syndrome

Bosnar,

Knežić Zagorec,

Bušić

et al. 2023

Trans. Vis. Sci. Tech.

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Idiopathic Organ Transplant Chorioretinopathy after Liver Transplantation

Abstract: Idiopathic organ transplant chorioretinopathy is a rare disease associated with kidney and heart transplantation. We present a case secondary to liver transplantation including its multimodal imaging, differential diagnosis, and physiopathology discussion.

Cited by 3 publications

References 16 publications

Choroidal and Retinal Abnormalities by Optical Coherence Tomography in Endogenous Cushing’s Syndrome

Choroidal and Retinal Abnormalities by Optical Coherence Tomography in Endogenous Cushing’s Syndrome

Giraffe or leopard spot chorioretinopathy as an outstanding finding: case report and literature review

Letter to the Editor: Characterization of Choriocapillaris and Choroidal Abnormalities in Alport Syndrome

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