The important cash crop of Chilli's (Capsicum annum L) production and yield is hampered by Chilli Leaf Curl Virus Disease (CLCVD) in Sri Lanka. To manage CLCVD several insecticides were promised against the vectors of CLCV. Indiscriminate use of insecticides created unwanted human health hazards. The current trends in plant pathology intend to boost the immunity of the host to increase the resistance against pathogens. Therefore, this study was conducted to investigate the efficacy of Sea-Weed Extract (SWE) to manage CLCVD. The chilli variety Vijaya was selected for this experiment with five treatments and a non-treated control, which were arranged in RBCD. Data on growth parameters, yield, aphid severity, and CLCV disease severity Index (DSI) were measured and subjected to ANOVA in SAS and Tukey's HSD multiple comparison test was used to identify the best treatment combination at P <0.05. The results showed that first application of Sea-Weed Extract (SEW) at 15 days after planting with subsequent application of SWE at 15 days interval + application of insecticides at 10-15 days interval (T4) significantly lowered the CLCV DSI of 40.24%, less aphid severity index of 5.16% with the highest chilli yield of 436.8 kg/ha. The investigation concluded that SWE induces plant immunity but no effect on vector control. Therefore, SWE with recommended insecticides is better to increase the immunity of plants for the effective management of CLCVD.