IgE levels in surgery: effect of ranitidine and prednisolone

Gt, Kampen; Poulsen, L K; Nielsen, Hans Jørgen; Schulze, Svend; Petersen, L. J.

doi:10.1034/j.1398-9995.1999.00775.x

Cited by 9 publications

(5 citation statements)

References 29 publications

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“…The full text was analyzed for 154 papers and 11 RCTs, spanning over 14 publications, were included. 13,26,27,[32][33][34][35][36][37][38][39][40][41][42] A PRISMA statement is shown in Figure 1 were noted in most RCTs with authors providing data regarding serum IL-6 levels and further clarification regarding outcomes where necessary. The authors of 9 of the trials were contacted.…”

Section: Trial Flowmentioning

confidence: 98%

Preoperative Glucocorticoid Use in Major Abdominal Surgery

Srinivasa

Kahokehr²,

Yu³

et al. 2011

Annals of Surgery

109

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Section: Trial Flowmentioning

confidence: 98%

Preoperative Glucocorticoid Use in Major Abdominal Surgery

Srinivasa

Kahokehr²,

Yu³

et al. 2011

Annals of Surgery

109

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“…In addition, it may be that the absence of adequate levels of cortisol could in part be responsible for the increased level of IgE. Glucocorticoids/corticosteroids are used to treat allergic patients and have been shown to lower serum IgE levels [17,18,27]. It is possible that normal cortisol levels are required to suppress IgE production.…”

Section: Discussionmentioning

confidence: 99%

Changes in Mucosal and Humoral Atopic-Related Markers and Immunoglobulins in Elite Cyclists Participating in the Vuelta a España

et al. 2006

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Atopic-related factors, humoral and mucosal immunoglobulins (Ig), and cortisol were measured in 17 professional cyclists competing in the 2003 Vuelta a España (a three-week multi-stage race). Venous blood and saliva samples were obtained the morning before the start of the race (T0), on the first rest day after 10 days of racing (T1), and before the start of the last stage after 21 days of racing (T2). Atopic-related factors, IgE, eosinophil cationic protein (ECP), and eosinophils, were significantly altered during the race. Serum IgE (T1: + 10 %) and ECP (salivary, T1: 113 % and serum, T2: 155 %) were significantly increased, while eosinophils (T1: - 32 %, T2: - 55 %) were significantly lower, than pre-race levels. Salivary sIgA secretion rate was significantly decreased at T2 (- 36 %). Pearson product-moment correlations revealed a modest correlation between salivary sIgA and salivary ECP (T1: r = 0.30; T2: r = 0.48; p < 0.01). Serum IgM, total IgG, IgG1, IgG2, IgA levels, at T1 and T2, and cortisol at T2, were significantly lower than pre-race levels. In conclusion, the elevation in IgE and ECP suggests an up-regulation of atopic-related factors in professional cyclists participating in the Vuelta a España. The correlation between salivary sIgA and salivary ECP indicates a role for sIgA in mediating mucosal inflammation. The alterations in Ig levels may indicate Ig isotype switching. An increasing state of hormonal fatigue may have influenced the observed immune alterations.

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“…Finally, we believe that the article by Kampen et al [18] had no relation to our objectives or discussion. Your work and publications seem to be mainly involved in the field of allergy and other contexts and for this reason are published in journals that specialize in these topics.…”

Section: Replymentioning

confidence: 91%