IgG4-related hepatic inflammatory pseudotumour: could MRI suggest the correct diagnosis?

Abstract

We report a case of a 62-year-old woman, HIV positive, with a 3-week history of jaundice and elevated cholestatic enzymes. Imaging studies displayed intrahepatic biliary dilatation and a central liver lesion. Pathology described lesions of active cholangitis, lymphoplasmacytic infiltration and fibrosis, suggesting a hepatic inflammatory pseudotumour (IPT) IgG4 related. IgG4-related lymphoplasmacytic form of IPT belongs to IgG4-related diseases. We discuss the importance to include IgG4-related hepatic IPT as part of the differential diagnosis of any liver lesion, highlighting potential imaging clues that may help in establishing the correct diagnosis.

Differential diagnosis of IgG4-related pancreatitis and pancreatic cancer by MRI features and its correlation with serum IgG4 level

“…diagnosis of benign and malignant lesions (14). MRI examination is mainly through the amount of hydrogen element content in the human body, in order to distinguish the corresponding image characteristics, and then through different image characteristics, to determine the corresponding organ function and the nature of the lesion, with the advantages of high resolution and high sensitivity (15). Serum IgG4 is the most common, commonly used, and effective early warning sign in clinical practice, and IgG4 is often investigated in patients with high suspicion of PC in clinical practice.…”