Ileal perforation due to typhoid fever – Review of operative management and outcome in an urban centre in Nigeria

Ugochukwu, A. I.; Amu, Okwudili C.; Nzegwu, M.A.

doi:10.1016/j.ijsu.2013.01.014

Cited by 53 publications

(64 citation statements)

References 7 publications

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“…The peak age group in this study was 11-20 years with about 65% of the patients being 20 years or younger when compared to Ugochukwu et al in Enugu that found the peak age to be 10-19 years [15]. The disease clinically presents with varying clinical features among such features are fever, abdominal pain, headache, abdominal distention and tenderness especially when perforation occurred.…”

Section: Discussionmentioning

confidence: 45%

Typhoid Perforation: Presentation and Management Outcome North-Eastern Nigeria

Aliyu¹,

Ud²,

Mb³

et al. 2017

J Gastrointest Dig Syst

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Section: Discussionmentioning

confidence: 45%

Typhoid Perforation: Presentation and Management Outcome North-Eastern Nigeria

Aliyu¹,

Ud²,

Mb³

et al. 2017

J Gastrointest Dig Syst

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“…In series 10 it was present in 75.6% cases and in the study 13 it was present in 50% patients. In our study Guarding was present in 41 patients (91%).…”

Section: Clinical Featuresmentioning

confidence: 59%

“…It was present in 90.4% of total patients in the study 12 . In study 16 vomiting was present in 66% patients while nausea and vomiting was present 70.9% in study 10 . In a similar study 13 , vomiting was present in 44% of patients.…”

Section: Clinical Featuresmentioning

confidence: 79%

“…In another study 9 a total of 42.7% of the patients were in the 21-30 years age group i.e., third decade of life In study by 10 58.1% of patients were within their second and third decades of life. While in other similar studies 11,12 the highest incidence of typhoid intestinal perforation occurred in the first and second decades of life with 83% and 47% respectively.…”

Section: Age Incidencementioning

confidence: 93%

“…In series 17 abdominal pain was seen in 60 (100%) patients and fever in 58 (96.6 %). Most of the patients presented with abdominal pain, (90.7%) in study 10 . And fever was present in 50.1% patients.…”

Section: Clinical Featuresmentioning

confidence: 94%

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A Clinical Profile of Typhoid Perforation of Bowel in a Tertiary Care Centre

Bhamre

Chandak

2016

mvpjms

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Background and Aims: Salmonella typhi causes an estimated 22 million cases of typhoid fever and 216000 deaths annually worldwide 1 and in developing countries, typhoid bowel perforation is an important surgical problem. The surgeon is faced with number of challenges during the management of these patients. The aims of this study are 1. To study the clinical profile of typhoid perforation of bowel in a tertiary care centre. 2. To study post operative outcome in patients with typhoid ulcer perforation. Methods and Methodology: A total of 45 patients diagnosed as having typhoid bowel perforation were included for the study after fulfilling the inclusion/ exclusion criteria. Results: Majority of patients were in the 2 nd and 3 rd decades (57.7%) with age ranging from 18 to 68 years. There were 28 (63.63%) males and 17 (37.7%) females. Fever with abdominal pain were the symptoms in all subjects followed by vomiting, distension of abdomen and constipation respectively. Most of the patients presented during 2 nd and 3 rd week of illness. 5 patients presented early i.e. within 24 hours and 40 patients presented late i.e., after 24 hours. Widal test was positive in 35 (79.45%) cases. Majority of patients (66.6%) group showed leucocytosis, while 7% showed leucopenia and 17% had normal WBC counts. Single perforation was found in 27 patients (60%), 2 perforations in 14 patients (31.1%) and more than 2 perforations were found in 4 patients (8.8%). Gas under diaphragm was present in all the patients. The most commonly done procedure in 33 cases (73.33% ) was simple closure of the perforation and resection and end to end ileo ileal anastomosis was done in 10 patients whereas ileo transverse anastomosis with ileostomy was done in 2 patients with multiple perforations. The most common post-operative complication was surgical site infection followed by respiratory infections, wound dehiscence. Enterocutaneous fistula was present in one case Mortality rate of 6.6 % was seen.

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Infection Management in Patients with Sepsis and Septic Shock in Resource-Limited Settings

Thwaites

Lundeg

Dondorp

et al. 2019

Sepsis Management in Resource-Limited Settings

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Hospital-and especially ICU-related infections are more likely to be caused by multidrug-resistant organisms, and previous antibiotic use is a risk factor for antibiotic resistance. Misdirected initial antibiotic therapy is associated with poor outcome [6,7], but there is a paucity of epidemiological data in most resource-limited settings. The aim of empirical antibiotic therapy is to treat the causative pathogen in the septic patient before definitive microbiological results are available. General principles guiding the choice of initial empirical antibiotic therapy apply to both resource-rich and resource-limited settings [8,9] and should take into consideration the pathogens and resistance patterns most likely to be encountered. This will depend on the suspected site and focus of the infection as well as healthcare setting

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Ileal perforation due to typhoid fever – Review of operative management and outcome in an urban centre in Nigeria

Cited by 53 publications

References 7 publications

Typhoid Perforation: Presentation and Management Outcome North-Eastern Nigeria

Typhoid Perforation: Presentation and Management Outcome North-Eastern Nigeria

A Clinical Profile of Typhoid Perforation of Bowel in a Tertiary Care Centre

Infection Management in Patients with Sepsis and Septic Shock in Resource-Limited Settings

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