Image-guided Radiation Therapy (IGRT) in Prostate Cancer: Preliminary Results in Prostate Registration and Acute Toxicity of a Randomized Study

Crevoisier, R. de; Pommier, P.; Bachaud, Jean-Marc; Créhange, G.; Boutry, C.; Chauvet, B.; Nguyen, T.D.; Laplanche, Agnès; Aubelle, Marie‐Stéphanie; Lagrange, J.L.

doi:10.1016/j.ijrobp.2009.07.242

Cited by 19 publications

(22 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…b) Data structuring: Each individual's 3DpDD is arranged in a vector by vertically concatenating the rows of all slices. Thus, we obtained an (N × P (1) ) matrix X (1) for patients with rectal bleeding and an (N × P (2) ) matrix X (2) for those without rectal bleeding: P (1) , P (2) and N represent the number of individuals with rectal bleeding, the number of individuals without rectal bleeding and the number of voxels, respectively.…”

Section: ) Preprocessing Stepmentioning

confidence: 99%

“…F (2) ), spanning two vector subspaces, A (1) and A (2) , that characterize patients with and without rectal bleeding, respectively. The dimensions F (i) (i = {1, 2}) are usually lower than P (i) .…”

Section: ) Preprocessing Stepmentioning

confidence: 99%

“…The dimensions F (i) (i = {1, 2}) are usually lower than P (i) . Secondly, we construct from A (1) and A (2) two sets of subspaces, called ε (1) = {ε…”

Section: ) Preprocessing Stepmentioning

confidence: 99%

“…Modern RadioTherapy (RT) techniques, such as Intensity Modulated RT (IMRT) and Image Guided RT (IGRT), may allow the increase of dose delivered to the target volume (tumor) [1] but at the expense of the risk of toxicity since neighboring organs may also be over-irradiated [2]- [4]. In the case of prostate cancer, the considered organs at risk are the bladder and the rectum for which the toxicity events may vary in time and complexity.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

A Novel Classification Method for Prediction of Rectal Bleeding in Prostate Cancer Radiotherapy Based on a Semi-Nonnegative ICA of 3D Planned Dose Distributions

Coloigner

Fargeas

Kachenoura

et al. 2015

IEEE J. Biomed. Health Inform.

View full text Add to dashboard Cite

The understanding of dose/side-effects relationships in prostate cancer radiotherapy is crucial to define appropriate individual's constraints for the therapy planning. Most of the existing methods to predict side-effects do not fully exploit the rich spatial information conveyed by the three-dimensional planned dose distributions. We propose a new classification method for three-dimensional individuals' doses, based on a new semi-nonnegative ICA algorithm to identify patients at risk of presenting rectal bleeding from a population treated for prostate cancer. The method first determines two bases of vectors from the population data: the two bases span vector subspaces, which characterize patients with and without rectal bleeding, respectively. The classification is then achieved by calculating the distance of a given patient to the two subspaces. The results, obtained on a cohort of 87 patients (at two year follow-up) treated with radiotherapy, showed high performance in terms of sensitivity and specificity.

show abstract

Section: ) Preprocessing Stepmentioning

confidence: 99%

Section: ) Preprocessing Stepmentioning

confidence: 99%

“…The dimensions F (i) (i = {1, 2}) are usually lower than P (i) . Secondly, we construct from A (1) and A (2) two sets of subspaces, called ε (1) = {ε…”

Section: ) Preprocessing Stepmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A Novel Classification Method for Prediction of Rectal Bleeding in Prostate Cancer Radiotherapy Based on a Semi-Nonnegative ICA of 3D Planned Dose Distributions

Coloigner

Fargeas

Kachenoura

et al. 2015

IEEE J. Biomed. Health Inform.

View full text Add to dashboard Cite

show abstract

“…Modern radiotherapy techniques include threedimensional conformal radiation therapy [1][2][3][4], intensitymodulated radiation therapy [5][6][7][8][9][10] and image-guided radiation therapy [11,12]. Current practice for radiation therapy involves optimisation of treatment plans using physical criteria (i.e.…”

mentioning

confidence: 99%

A novel correction factor based on extended volume to complement the conformity index

Jin

Wang²,

Yz³

2012

The British Journal of Radiology

View full text Add to dashboard Cite

Objective: We propose a modified conformity index (MCI), based on extended volume, that improves on existing indices by correcting for the insensitivity of previous conformity indices to reference dose shape to assess the quality of high-precision radiation therapy and present an evaluation of its application. Methods: In this paper, the MCI is similar to the conformity index suggested by Paddick (CI Paddick ), but with a different correction factor. It is shown for three cases: with an extended target volume, with an extended reference dose volume and without an extended volume. Extended volume is generated by expanding the original volume by 0.1-1.1 cm isotropically. Focusing on the simulation model, measurements of MCI employ a sphere target and three types of reference doses: a sphere, an ellipsoid and a cube. We can constrain the potential advantage of the new index by comparing MCI with CI Paddick . The measurements of MCI in head-neck cancers treated with intensity-modulated radiation therapy and volumetric-modulated arc therapy provide a window on its clinical practice.Results: The results of MCI for a simulation model and clinical practice are presented and the measurements are corrected for limited spatial resolution. The three types of MCI agree with each other, and comparisons between the MCI and CI Paddick are also provided. Conclusion:The results from our analysis show that the proposed MCI can provide more objective and accurate conformity measurement for high-precision radiation therapy. In combination with a dose-volume histogram, it will be a more useful conformity index.

show abstract

Nomograms to predict late urinary toxicity after prostate cancer radiotherapy

et al. 2013

View full text Add to dashboard Cite

show abstract

Image-guided Radiation Therapy (IGRT) in Prostate Cancer: Preliminary Results in Prostate Registration and Acute Toxicity of a Randomized Study

Cited by 19 publications

References 0 publications

A Novel Classification Method for Prediction of Rectal Bleeding in Prostate Cancer Radiotherapy Based on a Semi-Nonnegative ICA of 3D Planned Dose Distributions

A Novel Classification Method for Prediction of Rectal Bleeding in Prostate Cancer Radiotherapy Based on a Semi-Nonnegative ICA of 3D Planned Dose Distributions

A novel correction factor based on extended volume to complement the conformity index

Nomograms to predict late urinary toxicity after prostate cancer radiotherapy

Contact Info

Product

Resources

About