Imaging and Management of Breast Masses During Pregnancy and Lactation

Hogge, Jacquelyn P.; Paredes, Ellen Shaw de; Magnant, Colette; Lage, Janice M.

doi:10.1046/j.1524-4741.1999.98077.x

Cited by 53 publications

(38 citation statements)

References 25 publications

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“…Therefore, a careful breast examination at the first visit of pregnancy is important [9]. Similarly, malignant breast lesions could be mistakenly evaluated as benign and this would delay the correct diagnosis, resulting in more advanced disease [12]. …”

Section: Discussionmentioning

confidence: 99%

Malignant Phyllodes Tumor Including Aneurysmal Bone Cyst-Like Areas in Pregnancy - a Case Report and Review of the Literature

Kelten¹,

Boyacı²,

Leblebıcı³

et al. 2016

Breast Care

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Background: Malignant phyllodes tumors of the breast are rare biphasic neoplasms. Only few cases related to pregnancy have been reported. Case Report: A 37-year-old woman presented with swelling and pain in her left breast as well as hyperemia on the breast skin, 4 weeks after labor. In her family history, her aunt and maternal cousin had had a breast cancer diagnosis. Clinical evaluation of the patient was consistent with a breast abscess. Therefore, abscess drainage and biopsy from the cavity wall were performed. However, the biopsy was diagnosed as malignant phyllodes tumor. An evaluation by ultrasonography showed a well-defined hypoechoic mass with many cystic spaces covering the entire breast tissue. Therefore, a simple mastectomy was performed. Microscopic examination revealed a high-grade malignant phyllodes tumor. Additionally, bone cyst-like areas in the form of sponge-like blood-filled non-endothelialized spaces were observed. Conclusions: Since the breasts become larger due to the physiological changes during pregnancy, any underlying breast lesions may be obscured. Therefore, clinical breast examination in the first visit of pregnancy is important.

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Section: Discussionmentioning

confidence: 99%

Malignant Phyllodes Tumor Including Aneurysmal Bone Cyst-Like Areas in Pregnancy - a Case Report and Review of the Literature

Kelten¹,

Boyacı²,

Leblebıcı³

et al. 2016

Breast Care

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“…Iranian women, when being diagnosed with breast cancer, are at least 1 decade younger than the developed countries (1). The most common cancer in pregnancy and the most common cause of cancerrelated death in pregnant and breastfeeding women is breast cancer (2,3). Statistically, 1 case occurs per 3,000 pregnancies (4).…”

Section: Incidence Of Pabcmentioning

confidence: 99%

Pregnancy-associated Breast Cancer: A Review of Imaging Modalities

et al. 2018

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Context: The most common cancer and cause of cancer-related death in pregnant and breastfeeding patients is breast cancer. In the world, the incidence of pregnancy-associated breast cancer (P.A.B.C) is increasing, which is due to the fact that women delay their pregnancy up to the middle ages. According to the definition of P.A.B.C, a pregnancy-associated breast cancer is a case of breast cancer that occurs during pregnancy or up to 1 year after delivery. The aim of this paper is to review the clinical findings and novel imaging methods and findings, which help to diagnose pregnancy-associated breast cancer early. Evidence Acquisition: We reviewed the papers with subjects of PABC and imaging modalities in PABC by searching the medical and health databases such as PubMed, Google Scholar, as well as clinical trials. Results: The most frequent manifestation is a painless mass sensation. The most prevalent pathology of PABC is high-grade ductal carcinoma. The first diagnostic tool and most sensitive modality of imaging in this disease is ultrasound. Mammography during pregnancy and lactation is a safe method, which performs in symptomatic patients or in patients with positive ultrasound findings. MRI is not recommended during pregnancy, but it is completely harmless in breastfeeding patients and it is usually used as the complementary modality. Conclusions: Timely diagnosis of PABC requires complete knowledge of clinical symptoms and accurate interpreting of the images in different diagnostic modalities including mammography, ultrasound, and MRI. It should be noted that delay in diagnosis of PABC is the most common cause of low survival rate and bad prognosis.

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“…The cytology smears were studied with H and E staining, as well as Leishman's staining. The smears showed numerous, distinct, compact and semitransparent to dark blue/purple crystals on H and E staining [ The physiological changes of the breast during pregnancy and lactation make the clinical, radiological and the pathological evaluation of a breast mass particularly challenging [1].…”

mentioning

confidence: 99%