Imaging Appearances of Pseudoangiomatous Hyperplasia of Mammary Stroma

Burrows, C.; Loughran, C.F.

doi:10.1053/crad.1999.0104

Cited by 10 publications

(9 citation statements)

References 4 publications

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“…It is commonly associated with well-defined cystlike areas. 7,11,12,14,15 The lesion in our patient showed a comparable appearance, with dense isoechoic stroma, within which scattered cystic areas were seen. There have been limited MRI descriptions of PASH lesions in the literature.…”

Section: E Dsupporting

confidence: 59%

“…16 Another was described in a 34-year-old woman who had a large 13-cm tumoral mass. 15 This was a well-encapsulated lesion showing a predominantly intermediate signal with interspersed islands of lower-signal cystic areas on T1-weighted imaging and a mixed signal pattern with a low-signal intensity margin on T2-weighted imaging. 15 This differed from the lesion in our case, which extended into the surrounding normal breast parenchyma without a discernable capsule.…”

Section: E Dmentioning

confidence: 95%

“…15 This was a well-encapsulated lesion showing a predominantly intermediate signal with interspersed islands of lower-signal cystic areas on T1-weighted imaging and a mixed signal pattern with a low-signal intensity margin on T2-weighted imaging. 15 This differed from the lesion in our case, which extended into the surrounding normal breast parenchyma without a discernable capsule. The lesion in our case was composed of compact fibrous stroma and showed an intermediate signal, isointense to the surrounding breast parenchyma on both T1-and T2-weighted sequences.…”

Section: E Dmentioning

confidence: 95%

“…4,7,11,12 In a patient with large tumoral PASH, as in our case, mammography would show a uniform and marked increase in the density of the breast, and a discrete mass may be difficult to identify. 15 Sonographically, PASH is commonly hypoechoic in appearance, but isoechoic and hyperechoic textures have been described. It is commonly associated with well-defined cystlike areas.…”

Section: E Dmentioning

confidence: 99%

“…15 If the pathologic diagnosis of PASH on percutaneous core biopsy is consistent with the clinical and imaging findings, then surgical biopsy is not necessary. 11 If core biopsy results are not diagnostic or are suggestive of angiosarcoma, then surgical excision is warranted.…”

mentioning

confidence: 99%

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Rapidly Enlarging Tumoral Pseudoangiomatous Stromal Hyperplasia in a 15-Year-Old Patient

Teh

Chiang

Leung

et al. 2007

Journal of Ultrasound in Medicine

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seudoangiomatous stromal hyperplasia (PASH) is an uncommon benign lesion of the breast, with a relatively limited number of cases documented in the English literature.1 Breast tissue affected by PASH is characterized by dense myofibroblastic proliferation of mammary stroma, associated with interanastomosing capillarylike spaces.2,3 Pseudoangiomatous stromal hyperplasia may present in a wide clinicopathologic spectrum, ranging from focal minor incidental microscopic changes to clinically symptomatic and mammographically evident breast masses. 4,5 Most reported cases of PASH have been small to moderate-sized lesions. There have been few radiologic descriptions of large tumoral PASH. [5][6][7] We report a case of a 15-year-old patient with bilateral PASH presenting with rapid and massive asymmetric enlargement of the breasts. We describe its sonographic findings with correlative magnetic resonance imaging (MRI) and histopathologic features and highlight an unusual imaging feature not previously described.

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