Imaging manifestations of Behcet’s disease: Key considerations and major features

Brain miliary enhancement

“…7) [46]. In later stages, brainstem atrophy is a characteristic feature [42]. Furthermore, meningeal involvement, venous thrombosis and delayed intracerebral haemorrhages have been reported [42,44].…”

“…Behçet's disease is a multisystem inflammatory disease of unknown origin, presumably autoimmune in nature and mostly affecting patients from Japan or Mediterranean countries [42]. Onset before the age of 10 and after the age of 50 is rare.…”

“…Onset before the age of 10 and after the age of 50 is rare. The disease shows a male predominance in the Mediterranean region while women are more commonly affected in the Far East [42,43]. CNS involvement occurs in 10-30% of Behçet's patients, generally 4-6 years after the disease onset [42,44].…”

“…The disease shows a male predominance in the Mediterranean region while women are more commonly affected in the Far East [42,43]. CNS involvement occurs in 10-30% of Behçet's patients, generally 4-6 years after the disease onset [42,44]. The clinical presentation of systemic Behçet's disease shows recurrent oral aphthae (at least 3 times per year in 97% of cases), accompanied by any two of the following: genital ulcers which heal with scarring, erythema nodosum (in 60% of cases), folliculitis, uveitis, skin reactions and hyper-reactivity [42,45].…”

“…Neuro-Behçet's disease most commonly presents with bilateral pyramidal signs, hemiparesis and behavioural changes [42]. CSF findings are non-specific, revealing increased protein concentration and pleiocytosis [45].…”