Imaging of a Case of Extramedullary Solitary Plasmacytoma of the Trachea

Garelli, M.; Righini, C.A.; Faure, C; Jankowski, A.; Brambilla, Christian; Ferretti, G.

doi:10.1155/2011/687203

Cited by 5 publications

(20 citation statements)

References 8 publications

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“…[ 6 ] Squamous cell carcinoma and adenoid cystic carcinoma are the malignant tumors most common affecting the trachea. [ 7 ] EMP of the trachea, primarily occurring in 50-to-60-year-old male patients, represents around 3% of malignant tracheal tumors. [ 7 , 8 ] The pathogenesis of tracheal EMP is still unclear, but viral pathogenesis and chronic irritation may contribute to those lesions.…”

Section: Discussionmentioning

confidence: 99%

“…[ 7 ] EMP of the trachea, primarily occurring in 50-to-60-year-old male patients, represents around 3% of malignant tracheal tumors. [ 7 , 8 ] The pathogenesis of tracheal EMP is still unclear, but viral pathogenesis and chronic irritation may contribute to those lesions. [ 9 ] Airway obstruction is the most common symptoms of tracheal tumors.…”

Section: Discussionmentioning

confidence: 99%

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Extramedullary plasmacytoma of the trachea

Zhang

Su²,

Ran³

et al. 2018

Medicine

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Rationale:Extramedullary plasmacytomas (EMPs) are rare solitary soft tissue tumors characterized by monoclonal proliferation of plasma cells. Most lesions occur in the head and neck, but primary tracheal lesions are very rare.Patient Concerns:In this report, we describe a case of tracheal EMP discovered in a 48-year-old man who presented with a history of progressive dyspnea.Diagnoses:Computed tomography (CT) revealed a well-defined nodular mass in the posterior wall of trachea without signs of invasion of the tracheal walls. Then, a reddish mass occluding approximately 90% of the trachea was evidenced by bronchoscopic examination.Interventions:The patient was treated with surgery followed by adjuvant radiotherapy to achieve better local control.Outcomes:After the surgery, there was immediate symptomatic relief. There was no recurrence or metastasis during a 6-month follow-up.Lessons:This study presents a rare case of tracheal EMP occluding approximately 90% of the lumen that was successfully managed by surgery followed by radiotherapy.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Extramedullary plasmacytoma of the trachea

Zhang

Su²,

Ran³

et al. 2018

Medicine

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“…They constitute around 4% of all plasma cell neoplasms and in 80% of cases occur in the upper aerodigestive tract-nasal cavity, paranasal sinuses, and oronasopharynx. [ 1 2 3 ] Trachea is a very rare site of plasmacytoma. Less than twenty cases were reported in the medical literature until 2013.…”

Section: Introductionmentioning

confidence: 99%

Rare tracheal tumor

Stevic

Ercegovac

Stojšić

et al. 2018

Journal of Postgraduate Medicine

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Primary tracheal tumors are rare and trachea is an exceedingly rare site of extramedullary plasmacytoma (EMP). We report a case of solitary tracheal plasmacytoma causing symptoms of airway obstruction in a 59-year-old man. Flow/volume loop indicated the fixed central airway obstruction. Computerized tomography and bronchoscopy demonstrated a sessile tumor on posterior tracheal wall obstructing 80% of the lumen. Partial tracheal resection with T-T anastomosis was performed. Pathologic analysis of resected mass revealed EMP. Additional investigations excluded multiple myeloma. There are no signs of disease recurrence after 7-year follow-up.

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“…Involvement of the larynx, hypopharynx, cervical glands, esophagus, cervical lymph nodes, middle ear, and mastoid is rare (5) , and tracheal involvement is even rarer (5,11-13) , occurring in only 3% of all extramedullary plasmacytomas (9) . As of 2005, only 15 cases of solitary extramedullary plasmacytoma of the trachea had been reported in the medical literature (8) .…”

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confidence: 99%

“…Bronchoscopy correlates well with CT and can be used in order to resect the lesion (5,7) . The diagnosis is made through histological and immunohistochemical studies (5,14) . There was one reported case in which the tracheal plasmacytoma was identified as an incidental finding on positron emission tomography/CT (5) .…”

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confidence: 99%