Imaging principles and techniques in space-borne gamma-ray astronomy

Schönfelder, V.

doi:10.1016/j.nima.2004.03.029

Cited by 10 publications

(6 citation statements)

References 28 publications

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“…However, up to now, none of these Compton camera prototypes has been applied successfully in clinical practice. Compton cameras have been applied in astronomical research (Schönfelder 2004), but with completely different preconditions: longer measuring time, lower count rates, and 2D instead of 3D reconstruction. In this paper, the influence of the dimensions of the detectors on the reconstruction results is studied.…”

Section: Introductionmentioning

confidence: 99%

Requirements for a Compton camera forin vivorange verification of proton therapy

et al. 2017

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To ensure the optimal outcome of proton therapy, in vivo range verification is highly desired. Prompt γ-ray imaging (PGI) is a possible approach for in vivo range monitoring. For PGI, dedicated detection systems, e.g. Compton cameras, are currently under investigation. The presented paper deals with substantial requirements regarding hardware and software that a Compton camera used in clinical routine has to meet. By means of GEANT4 simulations, we investigate the load on the detectors and the percentage of background expected in a realistic irradiation and we simulate γ-ray detections subsequently used as input data for the reconstruction. By reconstructing events from simulated sources of well-defined geometry, we show that large-area detectors are favourable. We investigate reconstruction results in dependence of the number of events. Finally, an end-to-end test for a realistic patient scenario is presented: starting with a treatment plan, the γ-ray emissions are calculated, the detector response is modelled, and the image reconstruction is performed. By this, the complexity of the system is shown, and requirements and limitations regarding precision and costs are determined.

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Section: Introductionmentioning

confidence: 99%

Requirements for a Compton camera forin vivorange verification of proton therapy

et al. 2017

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“…To try to overcome this obstacle, a Compton photon imaging prototype is presented by Golnik et al [101] which measures prompt gamma emission, a side product of incident particle tissue interaction and associated dose deposition. Compton imaging seems to be a technique to measure three dimensional gamma emission profiles [102,103]. The Compton imaging prototype consists of two CZT cross streap detectors as scatterer and absorber.…”

Section: Active Photon Measurementsmentioning

confidence: 99%

Nuclear instrumentation and measurement: a review based on the ANIMMA conferences

Giot

Vermeeren

Lyoussi

et al. 2017

EPJ Nuclear Sci. Technol.

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Abstract. The ANIMMA conferences offer a unique opportunity to discover research carried out in all fields of nuclear measurements and instrumentation with applications extending from fundamental physics to fission and fusion reactors, medical imaging, environmental protection and homeland security. After four successful editions of the Conference, it was decided to prepare a review based to a large extent but not exclusively on the papers presented during the first four editions of the conference. This review is organized according to the measurement methodologies: neutronic, photonic, thermal, acoustic and optical measurements, as well as medical imaging and specific challenges linked to data acquisition and electronic hardening. The paper describes the main challenges justifying research in these different areas, and summarizes the recent progress reported. It offers researchers and engineers a way to quickly and efficiently access knowledge in highly specialized areas.

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“…Utilizing prompt gamma emission, a side product of particle tissue interaction opens the possibility of in-beam dose verification, due to the direct correlation between prompt gamma emission and particle dose deposition. Compton imaging has proven to be a technique to measure three dimensional gamma emission profiles ( [1], [2]) and opens the possibility of adaptive dose monitoring and treatment correction.…”

Section: Motivationmentioning

confidence: 99%