Imaging spectrum of renal oncocytomas: a pictorial review with pathologic correlation

Ishigami, Kousei; Jones, A.; Dahmoush, Laila; Leite, Leandro V.; Pakalniskis, Marius G.; Barloon, Thomas J.

doi:10.1007/s13244-014-0373-x

Cited by 48 publications

(25 citation statements)

References 30 publications

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“…Although it is widely believed that a central stellate scar is its main characteristic, it was reported present in only 46% of cases and may also appear in 26% of chRCC [38]. Moreover, there are overlapping imaging features between ccRCC and oncocytoma making their differentiation challenging [39]. Therefore, a reliable radiomics method that is non-reliant on the presence of a central scar to characterize oncocytomas would be an invaluable diagnostic tool.…”

Section: Oncocytoma Vs Rcc Subtypesmentioning

confidence: 99%

Radiomics Applications in Renal Tumor Assessment: A Comprehensive Review of the Literature

Suarez-Ibarrola

Basulto-Martínez

Heinze

et al. 2020

Cancers

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Radiomics texture analysis offers objective image information that could otherwise not be obtained by radiologists′ subjective radiological interpretation. We investigated radiomics applications in renal tumor assessment and provide a comprehensive review. A detailed search of original articles was performed using the PubMed-MEDLINE database until 20 March 2020 to identify English literature relevant to radiomics applications in renal tumor assessment. In total, 42 articles were included in the analysis and divided into four main categories: renal mass differentiation, nuclear grade prediction, gene expression-based molecular signatures, and patient outcome prediction. The main area of research involves accurately differentiating benign and malignant renal masses, specifically between renal cell carcinoma (RCC) subtypes and from angiomyolipoma without visible fat and oncocytoma. Nuclear grade prediction may enhance proper patient selection for risk-stratified treatment. Radiomics-predicted gene mutations may serve as surrogate biomarkers for high-risk disease, while predicting patients’ responses to targeted therapies and their outcomes will help develop personalized treatment algorithms. Studies generally reported the superiority of radiomics over expert radiological interpretation. Radiomics provides an alternative to subjective image interpretation for improving renal tumor diagnostic accuracy. Further incorporation of clinical and imaging data into radiomics algorithms will augment tumor prediction accuracy and enhance individualized medicine.

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Section: Oncocytoma Vs Rcc Subtypesmentioning

confidence: 99%

Radiomics Applications in Renal Tumor Assessment: A Comprehensive Review of the Literature

Suarez-Ibarrola

Basulto-Martínez

Heinze

et al. 2020

Cancers

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“…The degree of enhancement in contrast imaging and the timing of peak enhancement is variable in oncocytoma. [7] When the tumor is heterogeneously enhancing, it mimics clear cell type of renal cell carcinoma. When it presents as a hypovascular homogenous mass, it mimics chromophobe or papillary types of renal cell carcinoma.…”

Section: Discussionmentioning

confidence: 99%

Cystic renal oncocytoma mimicking renal cell carcinoma

2019

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Cystic renal lesions are one of the commonly encountered urological conditions. They can be either benign or malignant. The Bosniak classification is employed to differentiate benign cysts from the malignant ones and to recommend treatment options. Bosniak type 4 cysts are mostly malignant. Rarely, benign tumors can be encountered in Bosniak type 4 cysts. We present a 59-year-old female who presented with a hilar Bosniak type 4 cyst in the right kidney. She underwent open exploration of the right renal tumor. The tumor was infiltrating into the renal vessels and could not be separated from the renal vein. In view of preoperative and intraoperative suspicion of malignancy, radical nephrectomy was done. Postoperative histopathological examination revealed the tumor to be an oncocytoma. The benign nature of the cyst could not be conclusively determined by preoperative investigations and intraoperative findings. Postoperative histological examination uncovered the rare cystic presentation of this benign tumor.

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“…Renal oncocytosis is a recently established disease entity defined as diffuse replacement of the renal parenchyma by numerous oncocytic tumors, such as hybrid tumors, chromophobe RCCs, renal oncocytomas, and oncocytic renal parenchyma. [3542]…”

Section: Oncocytomamentioning

confidence: 99%

Solid renal masses in adults

Mittal

Sureka

2016

Indian Journal of Radiology and Imaging

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With the ever increasing trend of using cross-section imaging in today's era, incidental detection of small solid renal masses has dramatically multiplied. Coincidentally, the number of asymptomatic benign lesions being detected has also increased. The role of radiologists is not only to identify these lesions, but also go a one step further and accurately characterize various renal masses. Earlier detection of small renal cell carcinomas means identifying at the initial stage which has an impact on prognosis, patient management and healthcare costs. In this review article we share our experience with the typical and atypical solid renal masses encountered in adults in routine daily practice.

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Imaging spectrum of renal oncocytomas: a pictorial review with pathologic correlation

Cited by 48 publications

References 30 publications

Radiomics Applications in Renal Tumor Assessment: A Comprehensive Review of the Literature

Radiomics Applications in Renal Tumor Assessment: A Comprehensive Review of the Literature

Cystic renal oncocytoma mimicking renal cell carcinoma

Solid renal masses in adults

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