Solid renal masses in adults

Mittal, Mahesh Kumar; Sureka, Binit

doi:10.4103/0971-3026.195773

Cited by 26 publications

(17 citation statements)

References 70 publications

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“…The initial evaluation of parenchymal kidney lesions is usually done using B-mode US, which mainly distinguishes between cystic lesions and solid renal masses. For RCCs, gray scale US imaging shows an isoechoic or mildly hyperechoic, homogeneous or, especially for larger tumors, heterogeneous, solid parenchymal renal mass, with or without capsular bulging [ 37 ]. The additional use of color Doppler US allows for intra-tumor vascular distribution assessment and for additional quantification of RCC large vessel invasion, i.e., the detection of the characteristic RCC tumor thrombus extension, into the renal veins and/or inferior vena cava.…”

Section: The Role Of Current Imaging Modalities In Rcc Clinical Work-upmentioning

confidence: 99%

Contemporary Clinical Definitions, Differential Diagnosis, and Novel Predictive Tools for Renal Cell Carcinoma

Novacescu

Feciche²,

Cumpanas

et al. 2022

Biomedicines

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Despite significant progress regarding clinical detection/imaging evaluation modalities and genetic/molecular characterization of pathogenesis, advanced renal cell carcinoma (RCC) remains an incurable disease and overall RCC mortality has been steadily rising for decades. Concomitantly, clinical definitions have been greatly nuanced and refined. RCCs are currently viewed as a heterogeneous series of cancers, with the same anatomical origin, but fundamentally different metabolisms and clinical behaviors. Thus, RCC pathological diagnosis/subtyping guidelines have become increasingly intricate and cumbersome, routinely requiring ancillary studies, mainly immunohistochemistry. Meanwhile, RCC-associated-antigen targeted systemic therapy has been greatly diversified and emerging, novel clinical applications for RCC immunotherapy have already reported significant survival benefits, at least in the adjuvant setting. Even so, systemically disseminated RCCs still associate very poor clinical outcomes, with currently available therapeutic modalities only being able to prolong survival. In lack of a definitive cure for advanced RCCs, integration of the amounting scientific knowledge regarding RCC pathogenesis into RCC clinical management has been paramount for improving patient outcomes. The current review aims to offer an integrative perspective regarding contemporary RCC clinical definitions, proper RCC clinical work-up at initial diagnosis (semiology and multimodal imaging), RCC pathological evaluation, differential diagnosis/subtyping protocols, and novel clinical tools for RCC screening, risk stratification and therapeutic response prediction.

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Section: The Role Of Current Imaging Modalities In Rcc Clinical Work-upmentioning

confidence: 99%

Contemporary Clinical Definitions, Differential Diagnosis, and Novel Predictive Tools for Renal Cell Carcinoma

Novacescu

Feciche²,

Cumpanas

et al. 2022

Biomedicines

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“…13 The role of DWI MRI as a biomarker for the investigation of benign or malignant renal masses, subtypes of RCC, and histological grades is under evaluation. 7 There are several strengths and limitations to the use of MRI. MRI can be effective in the characterization of renal lesions when DMS and CT imaging methods are not sufficient.…”

Section: Magnetic Resonance Imagingmentioning

confidence: 99%

Comparison of Diagnostic Medical Sonography, Computed Tomography, Magnetic Resonance Imaging, and Contrast-Enhanced Ultrasound in the Investigation of Renal Lesions

Prince¹

2019

Journal of Diagnostic Medical Sonography

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This review explores the classification and evaluation of suspicious renal lesions across several radiologic imaging modalities. Diagnostic medical sonography (DMS), computed tomography (CT), magnetic resonance imaging (MRI), and contrast-enhanced ultrasound (CEUS) are the primary modalities used to investigate questionable lesions found within the kidneys. Renal masses may range from completely benign to malignant. They are classified based on many different features and characteristics. These lesions may be simple cystic, complex cystic, or solid in nature. Masses may also exhibit varying degrees of vascularity, septations, and calcifications. The discussed imaging modalities have varying strengths, limitations, and implications for use. Imaging techniques may be used independently or in conjunction to best diagnose and treat a patient with a suspicious renal mass. The aim of this review was to describe the diagnostic value of the imaging modalities (DMS, CT, MRI, and CEUS) and their role in the evaluation of suspicious renal lesions.

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“…2,3 Ultrasound (US)-and Computed tomography (CT)-guided percutaneous renal tumour biopsy (PRTB) is a common procedure following an incidental finding of an indeterminate renal mass on either a magnetic resonance (MR) or CT scan. 4 Studies have shown that PRTB prior to treatment is of high diagnostic value and a favourable option regarding subtype histopathological analysis of the presented renal mass in regard to accuracy and rate of complications. 5 Percutaneous renal tumour biopsy has been proven to be of use in an outpatient setting with a short post-biopsy observation time, when sudden onset complications are not present, proving it to be an efficient and reliable choice.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

One hour observation of patients after image-guided percutaneous renal mass biopsy

Valtersson

Rasmussen

Elgborn

et al. 2022

Acta Radiologica Open

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Background Imaging-guided percutaneous biopsy of renal masses is regarded as safe and is widely used for histopathology diagnosis before treatment. Recommended observation time after tumour biopsy varies in international guidelines and the literature is sparse. Purpose To assess the effect of a 1-h post-biopsy observation time of percutaneous image-guided renal mass biopsy. Material and Methods This was a single-centre retrospective study. During January 2015 to September 2019, a total of 484 patients underwent renal mass biopsies. 4-h-observation-group: 178 patients and 1-h-observation-group 306 patients. All records were retrospectively reviewed, and data such as complications was obtained and compared between the two groups. Results A total complication rate of 4.5% ( n = 22) without any major complications (Cardiovascular and Interventional Radiological Society of Europe-grade (CIRSE) 5–6). Furthermore, a non-significant difference of 1.3% of the 1-h group and 3.4% in the 4-h group experiencing complications was found ( p = .18). A total biopsy-accuracy of 84% was observed. Conclusion This study shows that renal mass biopsy is safe with no major complications. This suggests that an outpatient approach with 1-h-observation time can be safely implemented for renal mass biopsy.

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Solid renal masses in adults

Cited by 26 publications

References 70 publications

Contemporary Clinical Definitions, Differential Diagnosis, and Novel Predictive Tools for Renal Cell Carcinoma

Contemporary Clinical Definitions, Differential Diagnosis, and Novel Predictive Tools for Renal Cell Carcinoma

Comparison of Diagnostic Medical Sonography, Computed Tomography, Magnetic Resonance Imaging, and Contrast-Enhanced Ultrasound in the Investigation of Renal Lesions

One hour observation of patients after image-guided percutaneous renal mass biopsy

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