“…The grading for chondral lesions was described as having been performed using two difference systems. Sixteen studies assessed chondral lesions using a 0–4 grading system as suggested by Shahriaree [43], where 0 equated homogenous intermediate signal intensity and cartilage normal; 1 focal thickening of cartilage with smooth surface or cartilage loss/softening of cartilage; 2 equating to focal bulging, fissuring, blister lesions or shallow ulceration with mild surface irregularities; grade 3 equates to surface irregularities with deep ulceration or fibrillation not extending to subchondral bone; and grade 4 equating to cartilage defect with exposure of subchondral bone [3, 4, 9, 10, 14, 15, 17, 21, 25, 28, 35, 42, 44, 48, 49, 52]. Nine studies assessed grade of lesion using a 0–3 point scale as recommended by Noyes and Stabler [31], where grade 0 was normal cartilage; grade 1 was assigned to cartilage with minor surface irregularities with early fissuring but no loss of thickness; grade 2 signified cartilage thinning with deep fissures but no full‐thickness loss; and grade 3 equated to cartilage with at least one area of full‐thickness loss [1, 16, 19, 22, 29, 37, 38, 45, 46].…”