“…Magnetic resonance imaging (MRI) was investigated as a possible alternative method to detect and to evaluate vaccination-induced local reactions at the injection site in the living animal at several time points after vaccination. In human medicine imaging methods like MRI, computer tomography (CT) and ultrasound (US) are approved methods for clinical studies of muscular disorders like inflammation, denervation, mass lesions and their follow-up (Kuo and Carrino, 2007;Reimers, 1990;Schedel et al, 1992;Walker, 2008). Because of its higher sensitivity, a better contrast resolution and the use of non-ionizing radiation, MRI became the method of choice for soft tissue imaging (Fisher et al, 1986;Lovitt et al, 2006;Nägele and Hahn, 1990;Tanttu and Sepponen, 1996).…”