Imaging the major salivary glands

Burke, Christopher J.; Thomas, Robert H.; Howlett, D.C.

doi:10.1016/j.bjoms.2010.03.002

Cited by 157 publications

(112 citation statements)

References 29 publications

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“…Though FNAC is a readily available, low morbid and cost effective method of diagnosis in major salivary malignancy; the histological diversity of these tumors makes role of FNA controversial (Spiro, 1986;Schlakman and Yousem, 1993;Garden et al, 1997;Brennan et al, 2010). In terms of imaging, MRI remains the radiological tool of choice for assessment of deep lobe parotid tumors, patterns of infiltration and imaging of para-pharyngeal spaces while computed tomography (CT) is most effective when bony erosion is suspected (Armstrong et al, 1992;Burke et al, 2011). Role of ultrasound is limited to patients with superficial swellings of parotid and submandibular gland.…”

Section: Discussionmentioning

confidence: 99%

Ten Year Experience with Surgery and Radiation in the Management of Malignant Major Salivary Gland Tumors

Iqbal¹,

Bhatti²,

Hussain³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: Despite being rare in incidence, malignant tumors of major salivary glands show diverse histological variation. There are limited data on major salivary gland tumor management and outcome from Pakistan. The objective of this study was to share our experience with management of malignant tumors of major salivary glands. Materials and Methods: Patients who received treatment at Shaukat Khanum Cancer Hospital and Research Center from July 2002 to June 2011 with an underlying diagnosis of a major salivary gland malignancy were included. Patient characteristics and treatment modalities were assessed. Local, regional and distant failures were determined. Disease free survival (DFS) and overall survival (OS) were calculated using Kaplan Meier curves and the Log rank test was used to determine statistical significance. Univariate and multivariate analyses were performed using Cox proportional hazard regression. Results: The parotid gland was the primary site of origin in 104 (80%) patients. Mucoepidermoid carcinoma (43%) and adenoid cystic carcinoma (24%) were the most common histological types. Surgery followed by adjuvant radiation remained the mainstay treatment modality with 81 (62%) patients. Nineteen (15%) patients were treated with surgery alone and 30 (23%) patients with locally advanced surgically inoperable tumors received radiation only. Forty one (32%) patients failed the treatment (local 12, regional 11, locoregional 5, distant 13). The expected 5 year DFS and OS were 65% and 74% respectively. On multivariate analysis, grade was the only independent predictor of DFS and nodal involvement was the only independent predictor of overall survival. Conclusions: Employing existing standards of treatment, comparable survival can be achieved in Pakistani population with major salivary gland malignancies as elsehwere in the world.

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Section: Discussionmentioning

confidence: 99%

Ten Year Experience with Surgery and Radiation in the Management of Malignant Major Salivary Gland Tumors

Iqbal¹,

Bhatti²,

Hussain³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…Despite the high sensitivity of these radiological techniques, the accuracy of predicting histopathology of salivary gland masses is lower than expected as morphologic characteristics of benign and malignant lesions may overlap frequently (1)(2)(3)(4)(5)(6)(7). In addition, they have several limitations in daily practice.…”

Section: Introductionmentioning

confidence: 99%

Sonoelastographic Features of Major Salivary Gland Tumors and Pathology Correlation

Farasat¹,

Ovalı

Düzgün

et al. 2017

Iran J Radiol

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Objectives: To investigate the diagnostic efficiency of elastography in differentiation of malignant and benign tumors by evaluating salivary gland masses in means of their elastography scores and strain ratios. Patients and Methods: Twenty five patients with salivary gland mass lesions were detected through B-mode ultrasonography, Doppler ultrasonography, strain elastography and their strain ratios were calculated. The results were compared with histopathologic results. Results: Twenty five patients had 27 lesions consisting of seven malignant and 20 benign lesions. Mann Whitney U test, ROC analysis, Fisher test and Chi square tests were used statistically. Mean strain rates were calculated as 2.26 ± 0.29 in the benign group and 2.02 ± 0.59 in the malignant group. There was no statistically significant difference between the two groups (P = 0.698). Elastography score was calculated as mean 2.4 ± 0.94 in the benign group and mean 2.28 ± 0.38 in the malignant group. There was no statistically significant difference between the two groups (P = 0.708). Accepting the strain rate as 0.89; sensitivity of elastography in differentiating malignant from benign lesions is 71%, and the specificity is 50%. However, the area under the ROC curve is 0.55, which is not statistically significant (P = 0.699). Conclusion: Elastography is a supporting method for B-mode ultrasonography in the differentiation of benign and malignant salivary gland masses. However, the overlap of elastographic findings is evident in benign and malignant masses. Care should be taken to have tissues with similar stiffness under the reference tissue and the lesions in elastographic evaluation of the superficial mass. We have not met a study that has pointed out the importance of stiffness of the tissue located beneath the lesion that may affect the elastography results in the literature. In this respect our study is unique.

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“…[31] If the infection is not eliminated early, suppuration may After a culture is obtained, all patients should empirically be placed on a regimen of a penicillinase-resistant antibiotic such as semisynthetic penicillin. [32] A biopsy and retrograde sialography should be avoided.…”

Section: Bacterial Sialadenitismentioning

confidence: 99%

Reactive, Infectious and Benign Lesions of Salivary Gland- A Review

Singh¹

2017

WJPR

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Salivary gland tumors are relatively uncommon and account for approximately 3-6 percentage of all neoplasms of the head and neck.Tumors of salivary glands usually occur in the major salivary glands (parotid, submandibular, sublingual), however, a small percentage occur in the minor salivary glands located within the oral mucosa, palate, uvula, floor of the mouth, tongue, pharynx, larynx and paranasal sinuses. The salivary glands are subject to a number of pathologic conditions. These include inflammatory infective diseases such as viral, bacterial, or allergic sialadenitis, a variety of benign tumors. In this review we summarize the various reactive, infectious and benign lesions of salivary gland for better understanding with the recent references and current literature.

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Imaging the major salivary glands

Cited by 157 publications

References 29 publications

Ten Year Experience with Surgery and Radiation in the Management of Malignant Major Salivary Gland Tumors

Ten Year Experience with Surgery and Radiation in the Management of Malignant Major Salivary Gland Tumors

Sonoelastographic Features of Major Salivary Gland Tumors and Pathology Correlation

Reactive, Infectious and Benign Lesions of Salivary Gland- A Review

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