Imedeen® in the treatment of photoaged skin: an efficacy and safety trial over 12 months<sup>1</sup>

The topically applied cosmetic products can be helpful in improving the aged skin condition. The present study shows how oral fish-cartilage food supplementation can be helpful in improving the treatment of ageing skin. A total of 30 healthy women with signs of skin ageing were studied. Fifteen of the women were treated with a food supplement based on polysaccharides derived from the fish cartilage and a natural mix of antioxidants for 2 months and the other 15 with a placebo. Clinical evaluation and biophysical parameters related to skin function and wrinkle severity, such as silicone replica, skin thickness, mechanical properties, skin colour and capacitance, were measured. The results showed statistically significant changes in the active-treated group in comparison to the placebo. In particular, dermal thickness (treatment: from 1.13 to 1.23 mm; P < 0.001), skin wrinkling (treatment: from 9.5 to 3.5 R(a); P< 0.002), skin colour (treatment: brighter and less pigmented; P < 0.02) and viscoelasticity (treatment: from 0.70 to 0.97%; P < 0.02) showed considerable improvement. Most of these parameters are related to changes occurring within the dermal matrix, which is improved after the treatment, whereas most of the topically applied cosmetic products have a short-term effect on superficial structures. A combination treatment (oral and topical) can be more effective in reducing the signs of skin-ageing.

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Clinical and instrumental evaluation of a food supplement in improving skin hydration

Primavera

Berardesca

2005

Intern J of Cosmetic Sci

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Topically applied cosmetic products can be helpful in improving skin hydration. The study shows how oral supplementation could be helpful in improving and preventing the skin dehydration. A total of 32 healthy female volunteers entered the study. Of which, 16 were treated with a food supplement based on vegetable ceramides, amino acids, fish cartilage, antioxidants and essential fatty acids for 40 days and 16 with placebo. The results of the clinical and instrumental evaluations carried out in this study, have highlighted how the active treatment is effective in improving skin hydration and in reducing the cutaneous smoothness and roughness and the depth of furrows, in comparison to the placebo. In fact, concerning several important parameters, as stratum corneum hydration and skin roughness, the improvement measured exceeded 25%. We therefore suggest that a combination of treatments (oral and topical) can be more effective in improving skin hydration.

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Imedeen® in the treatment of photoaged skin: an efficacy and safety trial over 12 months¹

Abstract: Imedeen appears effective and safe for treatment of photoaged skin.

Cited by 10 publications

References 13 publications

Interventions for photodamaged skin

Interventions for photodamaged skin

Oral fish cartilage polysaccharides in the treatment of photoageing: biophysical findings

Clinical and instrumental evaluation of a food supplement in improving skin hydration

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Imedeen® in the treatment of photoaged skin: an efficacy and safety trial over 12 months1

Abstract: Imedeen appears effective and safe for treatment of photoaged skin.

Cited by 10 publications

References 13 publications

Interventions for photodamaged skin

Interventions for photodamaged skin

Oral fish cartilage polysaccharides in the treatment of photoageing: biophysical findings

Clinical and instrumental evaluation of a food supplement in improving skin hydration

Contact Info

Product

Resources

About

Imedeen® in the treatment of photoaged skin: an efficacy and safety trial over 12 months¹