Immediate neurotropic effects of ukrainian phytocomposition

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Background. Back in 2015, we registered short-term reactions to the Ukrainian phytocomposition of electroencephalogram and heart rate variability parameters. At the same time, we also recorded the reactions of biophotonics (GDV) parameters, but due to the skepticism of Ukrainian academic science regarding this method, we did not dare to include the results in the article. Materials and methods. The object of observation were 12 women (44±13 years) and 62 men (44±12 years) with dysfunction of neuro-endocrine-immune complex. GDV, HRV and EEG parameters were recorded in the morning in basal conditions. Then the members of the main group used 5 ml of phytocomposition dissolved in 45 ml of tap water, instead in the control group used 50 ml of the latter. After 1,5 hours, the test was repeated. Results. Discriminant analysis revealed 26 EEG, 6 HRV and 7 GDV parameters characteristic of the initial state and after consumption of phytocomposition or tap water. The use of balm causes the normalizing decrease of increased sympathotonic markers and the increase of decreased vagotonic markers. Physiologically favorable vegetotropic effects of the balm are accompanied by a further increase in the initially increased activity of β-rhythm-generating cortical and subcortical structures as well as activation of θ-rhythm-generating and inhibition of α- and δ-rhythm-generating nuclei whose initial activity was within normal limits. Neurotropic effects are accompanied by a decrease in fractality and entropy and an increase in the area of GDI, as well as the energy of the first, fourth, fifth and seventh chakras (virtual). Conclusion. Ukrainian phytocomposition “Balm Truskavets’” causes favorable immediate neurotropic and biophysic changes at patients with dysfunction of neuro-endocrine-immune complex.

“…Overall classification accuracy is 87,8% (Table 8). This is 6.7% higher than in our previous study [50]. The digital data of Table 5 are visualized in Figure 3.…”

Section: Variablescontrasting

confidence: 51%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Immediate effects of Ukrainian phytocomposition on biophotonics (GDV), EEG and HRV parameters

Ruzhylo

Żukow

et al. 2021

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“…In addition, calculated for HRV and each locus of EEG the Entropy (h) of normalized PSD using Popovych's IL [14,44] formulas based on classic Shannon's CE [47]…”

Section: Methodsmentioning

confidence: 99%

Features of EEG & HRV in 1997 in humans exposed to the factors of the accident at the Chornobylian nuclear power plant in 1986

Ruzhylo

Zakalyak

Ivanikiv

et al. 2022

Background. The dramatic events of the Russian-Ukrainian war around the Chornobyl’ nuclear power plant (NPP) once again opened up the healed wound inflicted by radionuclides on the human body not only in Ukraine, but also in Belarus and the border regions of Russia. The drama of the situation was further intensified by the events surrounding the Zaporizhzhia NPP. This prompted us to turn to the archive of the Truskavetsian Scientific School of Balneology and process the results of research that, due to certain technical and ethical circumstances, remained unanalyzed. Material and methods. The cohort of observation in 1997 were 19 men and 3 women who were exposed to pathogenic factors of the accident at the Chоrnobylian nuclear power plant during the liquidation of its consequences in 1986. The subject of the study was EEG and HRV parameters. The survey was conducted twice - on admission and after two weeks of rehabilitation at the Truskavets’ Spa. Results. Screening of the registered parameters revealed a pronounced sympathotonic shift of the autonomic balance, as well as a statistically significant deviation from the norm of 18 EEG parameters (increase in 8 and decrease in 10). Under the influence of two-week balneotherapy, 5 increased and 5 decreased EEG parameters normalized, but the remaining abnormal EEG and HRV parameters were resistant to the influence of balneofactors. Conclusion. Neurophysiological disorders, detected even 11 years after the effects of the factors of the Chornobyl’ disaster, differ both in severity and sensitivity to the sanogenic effect of the adaptogenic factors of the Truskavets’ Spa.

“…As, % = 100•(Max -Min)/Min; LI, % = Σ [200•(Right -Left)/(Right + Left)]/8. We calculated for HRV and each locus of EEG the Entropy (h) of normalized PSD using Popovych's IL [20,55] formulas based on classic Shannon's CE [57]…”

Section: Methodsmentioning

confidence: 99%

Relationships between plasma levels of nitrogenous metabolites and some psycho-neuro-endocrine parameters

Bombushkar

Гоженко

Корда

et al. 2022

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Background. It was recently shown by our group that bilirubin has a neurotropic activity. It is also shown that endogenous uric acid exerts a noticeable modulating effect on neuro-endocrine adaptation factors. In this study, we supplemented the constellation both of subjects of influence with other nitrogenous metabolites - urea and creatinine, and the objects of influence - with plasma levels of the main adaptation hormones and the severity of trait and reactive anxiety. Materials and Methods. The object of observation were almost healthy volunteers: 30 females (30÷76 y) and 31 males (24÷69 y). In basal conditions determined plasma levels of nitrogenous metabolites as well as cortisol, aldosterone, testosterone, triiodothyronine and calcitonin, estimated the severity of the trait and reactive anxiety, recorded the ongoing HRV and EEG. After 4 or 7 days, repeated testing was performed. Results. By constructing regression models, it was found that direct bilirubin determines the levels of psycho-neuro-endocrine parameters by 66,0%, free bilirubin by 56,7%, uric acid by 40,8%, creatinine by 37,6%, and urea - by 31,1%. Taken together, nitrogenous plasma metabolites determine the severity of trait, but not reactive anxiety, plasma levels of testosterone, cortisol and triiodothyronine, but not calcitonin and aldosterone, as well as a number of HRV and EEG parameters by 70,6%. Conclusion. Nitrogenous plasma metabolites, even in the absence of uremia, are able to influence the state of the psyche, autonomic and central nervous and endocrine systems, apparently through aryl hydrocarbon and adenosine receptors of neurons and endocrinocytes and/or directly.