Immobilization of Ytterbium by Plant Polyphenols for Antibiofilm Materials with Highly Effective Activity and Long-Term Stability

Abstract

The demand for innovative materials with favorable antiadhesion and antibiofilm abilities against bacteria has become imperative, given the increasing cognition of the harmfulness of biofilm colonization. Herein, typical plant polyphenols (PPs), including catechin, epigallocatechin gallate, and black wattle tannin (BWT), are utilized to catch and immobilize rare-earth ions onto the polyamide membrane to prepare advanced antibiofilm materials. The introduction of ytterbium (Yb) endows the polyamide membrane with excellent antiadhesion and antibiofilm abilities against Pseudomonas aeruginosa. The stability of Yb is improved by covalent immobilization by PPs. This effect significantly enhances the long-term antibacterial and antibiofilm activities under static and dynamic conditions. Furthermore, the Yb@BWT membrane exhibits the best antibacterial and antibiofilm performance among all prepared membranes with ∼100% inhibition for planktonic bacteria and biofilm formation after 2 days of soaking in artificial urine. The promising antibacterial and antibiofilm abilities of membranes prepared through the covalent immobilization of Yb by PPs indicate that the method reported here is a prospective facile, effective, and low-cost strategy for fabricating novel materials to prevent biofilm formation.

High-Value Utilization of Polyphenol Aromatic Antimicrobial Agents Extracted from Pineapple Peel Waste

“…With the increasing concern for environmental protection around the world, the search for naturally occurring, non-toxic, and sustainable antimicrobial agents has assumed greater importance. Natural substances called polyphenols derived from plants such as green tea, fruits, vegetables, and tree bark have significant antibacterial, antioxidant, and anticancer properties. , The extraction procedure of polyphenols is easy to use, environmentally friendly, and may safely be reintroduced into the ecosystem thereafter . It closely resembles the idea of sustainable green development. , Plant polyphenols already have a substantial impact on the food and healthcare sectors.…”

“…Natural substances called polyphenols derived from plants such as green tea, fruits, 5 vegetables, and tree bark have significant antibacterial, 6 antioxidant, 7 and anticancer properties. 8,9 The extraction procedure of polyphenols is easy to use, environmentally friendly, and may safely be reintroduced into the ecosystem thereafter. 10 It closely resembles the idea of sustainable green development.…”

“…It closely resembles the idea of sustainable green development. , Plant polyphenols already have a substantial impact on the food and healthcare sectors. Plant polyphenols including catechins, epigallocatechin gallate, and black wattle tannins have been found to have excellent resistance to Pseudomonas aeruginosa in the preparation of advanced anti-biofilm materials, and flavonoids are the main phenolic components used for the treatment of candidiasis . Polyphenol-rich cranberry extracts have been reported to have antibacterial activity against numerous Listeria species in food safety or freshness preservation .…”

Metal–Phenolic Networks for Chronic Wounds Therapy

“…Thus, Liu et al synthesized an antimicrobial membrane material by covalently bonding ytterbium ions (Yb 3+ ) to the plant polyphenols catechin (CAT), EGCG, and black catechin (BWT) and immobilizing them on a polyamide membrane, which can prevent biofilm-induced associated infections in a safe, inexpensive, and sustainable manner. 78…”