1988
DOI: 10.1111/j.1524-4725.1988.tb04041.x
|View full text |Cite
|
Sign up to set email alerts
|

Immunity to Injectable Collagen and Autoimmune Disease: A Summary of Current Understanding

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
6
0

Year Published

1988
1988
1999
1999

Publication Types

Select...
8
1

Relationship

1
8

Authors

Journals

citations
Cited by 22 publications
(6 citation statements)
references
References 73 publications
0
6
0
Order By: Relevance
“…Unfortunately, 1% to 6% of healthy patients receiving collagen injections experience a localized hypersensitivity reaction. [2][3][4] Usually this manifests as temporary erythema, pruritus, induration, and swelling. Granulomatous foreign body reactions have been reported by Overholt et al 5 and Moscana et al 6 Others 2,7 have documented the development of erythematous nodules at the injection sites, which can take up to 3 years to subside.…”
mentioning
confidence: 99%
“…Unfortunately, 1% to 6% of healthy patients receiving collagen injections experience a localized hypersensitivity reaction. [2][3][4] Usually this manifests as temporary erythema, pruritus, induration, and swelling. Granulomatous foreign body reactions have been reported by Overholt et al 5 and Moscana et al 6 Others 2,7 have documented the development of erythematous nodules at the injection sites, which can take up to 3 years to subside.…”
mentioning
confidence: 99%
“…Fortunately, these antibodies do not cross‐react with human collagen or other mammalian collagen, nor do they form immune complexes. Although there has been recent controversy over the possible association of dermatomyositis and other collagen vascular diseases to Zyderm, there are no convincing data to suggest any relationship 7,8 …”
mentioning
confidence: 99%
“…No autoimmune disease of any sort—dermatomyositis/polymyositis or any other—has ever been shown to arise on this basis. There are, in fact many diseases and traumatic injuries where anti‐human dermal collagen antibodies are present, such as periodontal disease and cirrhosis of the liver 13 —these antibodies have not been shown to provoke an autoimmune disease. In addition, there is no evidence that there is a correlation between the incidence of autoimmune disease in the general population and those who have natural antibodies to bovine collagen.…”
Section: Discussionmentioning
confidence: 99%