Immunization Status of Children Born to Human Immunodeficiency Virus (HIV)-Infected Mothers in Two Texas Cities

Schulte, Joann; Burkham, Susan; Squires, Janet E.; Doran, Terence I.; Hamaker, Douglas; Pelosi, Jan W.; Graper, Janeen; Davis, Rachel; Caldwell, M. Blake

doi:10.1097/00007611-200093010-00009

Cited by 13 publications

(2 citation statements)

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“…Like ours, recent Swiss and Spanish studies found lower immunization coverage in this population than in the general public [3,4]. A study from Texas found no difference between HIV-infected patients and the general population for diphtheria, tetanus, acellular pertussis and inactivated polio vaccine (DTaP-IPV) and MMR, although vaccine coverage was low overall [5].…”

supporting

confidence: 62%

Immunization status of children with HIV: failure to protect a vulnerable population

Zinna¹,

Bamford²,

Cunnington³

et al. 2011

HIV Medicine

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supporting

confidence: 62%

Immunization status of children with HIV: failure to protect a vulnerable population

Zinna¹,

Bamford²,

Cunnington³

et al. 2011

HIV Medicine

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“…Previous studies of pertussis using linked data have predominately focused on aspects of pertussis vaccination such as vaccine safety [6–8], vaccine uptake [9, 10], and the validity of linked data for vaccine effectiveness studies [11, 12]. Fewer studies have examined risk factors for infection [13–15] and long-term consequences of infection [16].…”

Section: Introductionmentioning

confidence: 99%

Estimating the burden of pertussis in young children on hospitals and emergency departments: a study using linked routinely collected data

et al. 2013

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Potential underestimation of the health system burden of pertussis was investigated by linking administrative datasets including pertussis notifications, hospitalizations and emergency department (ED) presentations for 1 304 876 children aged <15 years in NSW, Australia. From 2005 to 2008, 3006 children had a pertussis notification, 455 were hospitalized and 644 had an ED presentation with a coded diagnosis of pertussis. Linking hospital and ED records with pertussis notifications identified 140 hospitalizations and 735 ED presentations which occurred ± 7 days from notification but did not have a diagnosis of pertussis recorded. These additional events were more likely to have a diagnosis of bronchiolitis, upper respiratory infection and cough compared to all other admissions and presentations. Including these additional events significantly increased the proportion of notified cases that were hospitalized or visited EDs, particularly for those aged 5 to <15 years. Linked administrative data allowed more comprehensive estimation of the health system burden of pertussis.

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Immunisation coverage among children born to HIV-infected women in Rakai district, Uganda: effect of voluntary testing and counselling (VCT)

et al. 2006

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To evaluate the impact of maternal HIV-infection on routine childhood Immunisation coverage, we compared the Immunisation status of children born to HIV-infected and HIV-uninfected women in rural Uganda. The study population was 214 HIV(+) and 578 HIV(-) women with children aged 6 to 35 months previously enrolled in a community study to evaluate maternal and child health in Rakai District, Uganda. Sampling of subjects for interview was stratified by the use of voluntary counselling and testing (VCT) service so that the final sample was four groups: HIV + /VCT+ (n = 98); HIV + /VCT- (n = 116); HIV - /VCT+ (n= 348); HIV - /VCT- (n = 230). The main outcome measure was the percent of complete routine childhood Immunisations recommended by the WHO as assessed from Immunisation cards or maternal recall during household interviews. We found that Immunisation coverage in the overall sample was 26.1%. For all vaccines, children born to HIV-infected mothers had lower Immunisation coverage than children born to HIV-negative mothers (21.3 vs. 27.7%). There was a statistically significant interaction between maternal HIV-infection and maternal knowledge of HIV-infection (p = 0.034). The children of mothers who were HIV-infected and knew their serostatus (HIV + /VCT + ) had a more than two-fold odds of underImmunisation (OR = 2.21, 95% CI: 1.14, 4.29) compared to children of mothers who were HIV - /VCT-. We conclude that maternal HIV-infection was associated with childhood underImmunisation and this was mediated by a mother's knowledge of her HIV status. HIV VCT programmes should encourage HIV-infected mothers to complete childhood Immunisation. Improving access to Immunisation services could benefit vulnerable populations such as children born to HIV-infected mothers.

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Immunization Status of Children Born to Human Immunodeficiency Virus (HIV)-Infected Mothers in Two Texas Cities

Cited by 13 publications

References 0 publications

Immunization status of children with HIV: failure to protect a vulnerable population

Immunization status of children with HIV: failure to protect a vulnerable population

Estimating the burden of pertussis in young children on hospitals and emergency departments: a study using linked routinely collected data

Immunisation coverage among children born to HIV-infected women in Rakai district, Uganda: effect of voluntary testing and counselling (VCT)

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