Immunodeficiency-Associated Burkitt’s lymphoma in pediatric patients: a clinical case report

Abstract

Burkitt's lymphoma, a form of non-Hodgkin lymphoma, is a neoplastic monoclonal proliferation of lymphoid cells in areas of the immune system. It can occur in HIV-positive patients, as AIDS is related to the development of non-Hodgkin lymphoma. Burkitt's lymphoma is a rare subtype, highly prevalent in patients with AIDS. Incisional biopsy, in situ hybridization and computerized axial tomography are the appropriate tests to determine the characterize of the lesions. The case of a 4-year-old HIV-positive patient, who developed Burkitt's lymphoma of the oral cavity, is reported in this paper. The aim of this case report is to describe the course of the pathology, taking into account its clinical imaging characteristics and treatment.

An 8-year retrospective study of adult and paediatric Burkitt’s lymphoma at Tygerberg Hospital, South Africa

“…There are few case reports of children with immunodeficiencyassociated BL in the world. 54,55,56 The sample size of HIV-negative adults (n = 4) could not be reliably analysed and additional research is required. An international study of 52 immunocompetent adults with BL showed an event-free survival rate of 65% at 2 years.…”

Primary nasopharyngeal Burkitt’s lymphoma in paediatric patients in a non-endemic region: our experience

“…Timely and accurate diagnosis of the BL is challenging but crucial. The standard treatment of BL in paediatric age is chemotherapy, but sometimes surgery may be added [8]. In this study, we discuss the clinical profile, management, and outcome of nasopharyngeal BL in paediatric age at a tertiary care teaching hospital in eastern India.…”