Immunoglobulin genes and antibody responses in the spotted wolffish (Anarhichas minor Olafsen)

Distribution of IgM, IgD and IgZ in mandarin fish, Siniperca chuatsi lymphoid tissues and their transcriptional changes after Flavobacterium columnare stimulation

“…In channel catfish it was showed that serum and mucus Ig concentrations increased markedly at about 2 weeks post infection with Edwardsiella ictaluri (Zilberg and Klesius, 1997). In spotted wolffish immunization with bacteria induced hightitered antibody responses (Espelid et al, 2001). In the present study intensive up-regulation of IgM transcripts was detected by real time PCR, which proves that stimulation causes the increase of IgM transcripts.…”

Molecular cloning of IgZ heavy chain isotype in Catla catla and comparative expression profile of IgZ and IgM following pathogenic infection

“…Taken together, these findings suggest that, along with Cc IgM, Cc IgZ plays a crucial role in eliciting humoral immunity by triggering neutralizations of antigens. Similar conclusions have been reported for channel catfish , mandarin fish , spotted wolffish and common carp .…”

Three isotypes of immunoglobulin light chains in large yellow croaker, Pseudosciaena crocea: Molecular cloning, characterization, and expression analysis

“…Generally, the IgLk isotype is more abundant in teleost than the IgLs and l isotypes. The teleost IgL1, IgL2, and IgL3 have been identified in rainbow trout Oncorhynchus mykiss [3,4,16], Atlantic salmon Salmo salar [17], spotted wolfish Anarhicas minor [18,19], green pufferfish Tetraodon nigroviridis [20], common carp Cyprinus carpio [21,22,23], and zebrafish Danio reio [24,25]. From an evolutionary point it is favorable having more than one isotype or light chain locus so that IgLs can successfully rearrange to contribute to the variability of immunoglobulins.…”