Immunolocalization of atrial natriuretic peptide in mast cells of human and rat pericardium

Martynova, Marina G.; Nakatseva, E. V.; Emeljanova, O. I.; Moiseeva, O. M.; Erokhina, I. L.

doi:10.1134/s1990519x08010033

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“…In addition, a recent study in rat and human pericardial fluid demonstrated ANP-immunopositivity in mast-cells of the connective tissue [7]. The ANP immunopositivity in myocardiocytes demonstrated that also in Ciona ANP is present and that ANP might play the same role of the specific granules of different animal species.…”

Section: Discussionmentioning

confidence: 99%

ANP (Atrial Natriuretic Peptide) presence in the heart of a tunicate, Ciona intestinalis.

Lipari

Gerbino

Lipari³

et al. 2010

Folia Histochem Cytobiol.

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Atrial natriuretic peptide was found in the heart of vertebrates, we studied the ANP presence in the heart of Ciona intestinalis. This is animal is very important because of the its evolutionary position between invertebrates and vertebrates. ANP presence was only revealed in myoepithelial cells of the myocardium. Results suggest the hypothesis that ANP is present not only in the vertebrates but also in the invertebrates and in Ciona heart ANP might play a similar role like in the heart of vertebrates.

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Section: Discussionmentioning

confidence: 99%