2014
DOI: 10.18410/jebmh/2014/301
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Immunological Causes of Bad Obstetric History

Abstract: Occurrence of three consecutive pregnancy losses constitutes the classic definition of bad obstetric history (BOH). One of the important causes of BOH is the presence of antiphospholipid antibodies, which enhance the coagulability of blood in pregnancy. The association between phospholipid antibodies and recurrent miscarriage is called Antiphospholipid Syndrome (APS). Pregnant women with thrombotic APS have higher rates of pregnancy complications. APS is responsible for first trimester pregnancy loss in 90% of… Show more

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Cited by 6 publications
(4 citation statements)
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“…Poor obstetrics history: if a woman had experienced any of the following events on two or more occasions in the past: consecutive spontaneous abortions, early neonatal deaths, stillbirths, intrauterine fetal deaths, intrauterine growth retardation, congenital anomalies in the fetus [16].…”
Section: Operational Definitionsmentioning
confidence: 99%
“…Poor obstetrics history: if a woman had experienced any of the following events on two or more occasions in the past: consecutive spontaneous abortions, early neonatal deaths, stillbirths, intrauterine fetal deaths, intrauterine growth retardation, congenital anomalies in the fetus [16].…”
Section: Operational Definitionsmentioning
confidence: 99%
“…BOH implied previous unfavorable fetal outcomes, such as 3 or more successive spontaneous abortions, early neonatal deaths, stillbirths, intrauterine growth restriction (IUGR) and congenital anomalies in the previous pregnancies. 6 The results were analyzed using SPSS (version 22). Chi square test was applied as a test of significance and p value of < 0.05 was considered as statistically significant.…”
Section: Exclusion Criteriamentioning
confidence: 99%
“…However, it is the occurrence of three consecutive pregnancy losses that constitutes the classic definition of BOH. This condition is seen in 1-2% of couples [2] . RCOG Guidelines [3] defines recurrent miscarriage as the loss of three or more consecutive pregnancies, however, The Practice Committee of the American Society for Reproductive Medicine [4] defines recurrent pregnancy loss as two or more failed pregnancies.…”
Section: Introductionmentioning
confidence: 98%