Immunology of the Newborn Calf: Its Relationship to Colisepticemia*

Fey, H.

doi:10.1111/j.1749-6632.1971.tb34992.x

Cited by 39 publications

(14 citation statements)

References 27 publications

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“…Because the amount adsorbed in the first 12 h directly depends on the concentration of the ingested Igs , piglets that suckle first at 12 h obtain threefold less Ig in blood. Morbidity and mortality among suckling ungulates can be traced to low blood immunoglobulin levels (Fey, 1971;Logan et al, 1974) such as in severe combined immunodeficiency Arabian horses (McGuire et al, 1976(McGuire et al, , 1977, resulting from a delay in suckling and/or the availability of Igs in lacteal secretions.…”

Section: The Mechanism and Consequences Of Gut Closurementioning

confidence: 99%

The Mammary Gland in Mucosal and Regional Immunity

et al. 2015

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Section: The Mechanism and Consequences Of Gut Closurementioning

confidence: 99%

The Mammary Gland in Mucosal and Regional Immunity

et al. 2015

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“…Since the importance of colostrum for the survival of the calf has been established (1,9,15), an evaluation of the three vaccines for production of protective factors in colostrum would be an appropriate indication of vaccine efficiency. Since colostrum-derived antibody had been shown by many investigators to be a critical factor in passive immunity in neonatal calves (2,3,26), it would follow that an effective vaccine should elicit protective antibodies that will predominate in the dam's colostrum.…”

Section: Resultsmentioning

confidence: 99%

Experimental neonatal colibacillosis in cows: serological studies

Wilson¹,

Jutila²

1976

Infect Immun

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Serological studies of passive immunity in experimentally induced bovine colibacillosis was studied in a 41-cow university herd. Pregnant dams were antigenized prepartum with two injections administered by the subcutaneous and intrammamary routes with one of four vaccine preparations (killed bacteria, live bacteria, culture supernatant, or heart infusion broth [control]). The data indicate that 77% of the neonates born to vaccinated dams were strongly protected against oral challenge with Escherichia coli strain B-44. Bacterial agglutinin and passive hemagglutination titers of colostral whey directly reflected the efficacy of the vaccines. A notable decrease in the whey titers to somatic and capsular antigens occurred after heat treatment at 56 C for 30 min. Complicity of heat-liable immune factor(s) in protection from scouring was suggested. The nature of the protective antigen is not clearly defined by these studies but there is some evidence that the K antigen may play a vital role in this regard.

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“…61,62 Abomasal pH of the calf is 4.4 at birth 63 and after colostrum ingestion ranges from 5.9 to 7.2 over the first 20 hours of life. 64 The mean preprandial pH is constant between 1.4 and 1.7 after day 5 of life. 65,66 The relatively high pH during the first day of life ensures ingested colostral immunoglobulins are minimally degraded before arriving in the small intestine, which is the site of immunoglobulin absorption.…”

Section: Increasing Nonspecific Resistancementioning

confidence: 99%

Treatment of Calf Diarrhea: Antimicrobial and Ancillary Treatments

Constable

2009

Veterinary Clinics of North America: Food Animal Practice

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Adjunct treatment of diarrhea should be routinely undertaken in all calves with systemic signs of illness, manifest as fever, inappetance, or lethargy. Ancillary treatments with documented efficacy in undifferentiated calf diarrhea include parenteral administration of antimicrobials with a predominantly gram negative spectrum of activity, parenteral administration of non-steroidal anti-inflammatory agents such as meloxicam and flunixin meglumine, and continued feeding of cow's milk. Halofuginone and azithromycin have efficacy in calves with diarrhea due to Cryptosporidium parvum, and their administration should be considered in calves documented or suspected to have cryptosporidiosis.

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Immunology of the Newborn Calf: Its Relationship to Colisepticemia*

Cited by 39 publications

References 27 publications

The Mammary Gland in Mucosal and Regional Immunity

The Mammary Gland in Mucosal and Regional Immunity

Experimental neonatal colibacillosis in cows: serological studies

Treatment of Calf Diarrhea: Antimicrobial and Ancillary Treatments

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