Immunomodulatory Activity of Swarna Prashana in Charle’s Foster Albino Rats

Khedekar, Sanjay; Priya, Anu; Patgiri, B; Nariya, M; Prajapati, PK

doi:10.5530/jams.2016.1.12

Cited by 8 publications

(6 citation statements)

References 4 publications

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“…The effects of the Ayurvedic gold preparation SwarnaBhasma (SB) -auranofin (AN) and the Unani preparation KushtaTilaKalan (KTK) on nonspecific immunity were investigated in a study where the incremental doses of these medicines were given orally to male mice for ten days. Both test medications (KTK and SB) significantly (P<0.001) raised peritoneal macrophage numbers and enhanced macrophage phagocytic index, whereas AN had a suppressive effect on these parameters 22 .…”

Section: Pharmacological Actions: Immunomodulatory Effect Of Swarnapr...mentioning

confidence: 92%

Untitled

2023

IJPSR

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Introduction: Gold preparations are highly prized and often utilized for their tonic and revitalizing effects in Indian systems of medicine. Gold has both preventive and curative medicinal properties. The Kashyap Samhita, under the name Swarnaprashana, describes the usage of gold internally in children via the oral route. After birth, it is indicated in Lehan karma (supplementary feeding to improve nutrition, immunity and intelligence) and Jatkarma (newborn care). Now a day Swarnaprashana in children is getting huge publicity, and many trials are being conducted to evidence its use in children. Material and Methods: This review is in a narrative format and consists of all publications relevant to Swarnaprashana or Swarnabinduprashana, Suvarnabindu prashan, Suvarnavachayog, or Swarnavachayog that the authors identified through a systematic search of major computerized medical databases; no statistical pooling of results or evaluation of the quality of the studies was performed due to the widely different methods employed by each study. Result and Discussion: The present review of the studies proves the role of Swarnaprashana in enhancing cognition and protection against diseases by enhancing immunity. Swarnaprashana acts on multiple levels and can be given for better growth and development in children. Swarnaprashana is safe for children. Conclusion: Clinical and pharmacological studies show immunomodulatory, nootropic, and therapeutic effects of Swarnaprashan as therapy.

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Section: Pharmacological Actions: Immunomodulatory Effect Of Swarnapr...mentioning

confidence: 92%

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2023

IJPSR

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“…As a result, anti-inflammation medicines are effective against COVID-19. Many Bhasma remedies have anti-inflammatory qualities; therefore, it can be assumed that Rajata Bhasma (Silver nanoparticles), Yashada Bhasma (Zinc nanoparticles), and Tamra Bhasma (Copper nanoparticles) will be useful in fighting with COVID-19 [ 177 ]. According to the World Health Organization (WHO), patients with COVID-19 infection had higher levels of plasma cytokines, interferons alpha (IFN), interferons gamma (IFN), and tumour necrosis factor-alpha (TNF).…”

Section: Biomedical and Other Application Of Zno Npsmentioning

confidence: 99%

Biogenic Zinc Oxide Nanoparticles and Their Biomedical Applications: A Review

Jha

Rani

Singh

2023

J Inorg Organomet Polym

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Nanotechnology has inscribed novel perception into the material science and one of the most extensively used nanomaterials is Zinc oxide nanoparticles (ZnO NPs) with healthcare and biomedical applications. Because of its outstanding biocompatibility, low toxicity, and low cost, ZnO NPs have become one of the most prominent metal oxide NPs in biological applications. This review highlights the different aspects of ZnO NPs, like their green synthesis as a substitute of conventional route due to avoidance of threat of hazardous, costly precursors and subsequent mostly therapeutic applications. Due to their wide bandwidth and high excitation binding energy, ZnO NPs have undergone extensive research. In addition to their potential applications as antibiotics, antioxidants, anti-diabetics, and cytotoxic agents, ZnO NPs also hold a promising future as an antiviral treatment for SARS-CoV-2. Zn has antiviral properties and may be effective against a variety of respiratory virus species, particularly SARS-CoV-2. This review includes a variety of topics, including the virus’s structural properties, an overview of infection mechanism, and current COVID-19 treatments. Nanotechnology-based techniques for the prevention, diagnosis, and treatment of COVID-19 are also discussed in this review.

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“…Swarna Bhasma also decreases cytokine secretion and affects T-cell activity, thereby promoting vasodilation. 351 Tamra Bhasma has been reported to have significant inflammatory inhibitory activity by reducing the production of IL-6 and TNF-α. 131,352 13 | PROSPECTS AND CONCLUSIONS…”

Section: Lung Targeted Nanomedicine Deliverymentioning

confidence: 99%

COVID‐19 cooling: Nanostrategies targeting cytokine storm for controlling severe and critical symptoms

Zheng,

Li,

et al. 2023

Medicinal Research Reviews

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As severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants continue to wreak havoc worldwide, the “Cytokine Storm” (CS, also known as the inflammatory storm) or Cytokine Release Syndrome has reemerged in the public consciousness. CS is a significant contributor to the deterioration of infected individuals. Therefore, CS control is of great significance for the treatment of critically ill patients and the reduction of mortality rates. With the occurrence of variants, concerns regarding the efficacy of vaccines and antiviral drugs with a broad spectrum have grown. We should make an effort to modernize treatment strategies to address the challenges posed by mutations. Thus, in addition to the requirement for additional clinical data to monitor the long‐term effects of vaccines and broad‐spectrum antiviral drugs, we can use CS as an entry point and therapeutic target to alleviate the severity of the disease in patients. To effectively combat the mutation, new technologies for neutralizing or controlling CS must be developed. In recent years, nanotechnology has been widely applied in the biomedical field, opening up a plethora of opportunities for CS. Here, we put forward the view of cytokine storm as a therapeutic target can be used to treat critically ill patients by expounding the relationship between coronavirus disease 2019 (COVID‐19) and CS and the mechanisms associated with CS. We pay special attention to the representative strategies of nanomaterials in current neutral and CS research, as well as their potential chemical design and principles. We hope that the nanostrategies described in this review provide attractive treatment options for severe and critical COVID‐19 caused by CS.

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Immunomodulatory Activity of Swarna Prashana in Charle’s Foster Albino Rats

Cited by 8 publications

References 4 publications

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Biogenic Zinc Oxide Nanoparticles and Their Biomedical Applications: A Review

COVID‐19 cooling: Nanostrategies targeting cytokine storm for controlling severe and critical symptoms

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