2000
DOI: 10.1016/s0378-8741(99)00206-8
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Immunomodulatory activity of Withania somnifera

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Cited by 244 publications
(155 citation statements)
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“…In this context, sheep red blood cells (SRBCs) have been widely employed as antigens for eliciting anti-SRBC antibody titers in rats (Sharma et al, 1994;Davis & Kuttan, 2000;Tiwari et al, 2004). In the present investigation, we used fresh sheep blood collected in Alsever's solution from Haffkine Biopharmaceuticals, Mumbai, India as the source of SRBCs for eliciting humoral responses in rats.…”
Section: Chemicals and Reagentsmentioning
confidence: 99%
“…In this context, sheep red blood cells (SRBCs) have been widely employed as antigens for eliciting anti-SRBC antibody titers in rats (Sharma et al, 1994;Davis & Kuttan, 2000;Tiwari et al, 2004). In the present investigation, we used fresh sheep blood collected in Alsever's solution from Haffkine Biopharmaceuticals, Mumbai, India as the source of SRBCs for eliciting humoral responses in rats.…”
Section: Chemicals and Reagentsmentioning
confidence: 99%
“…There is growing interest in identifying and characterizing insects with immunomodulatory activity. Immunoregulation is a complex balance between regulatory and effector cell and any imbalance in the immunological mechanism can lead to pathogenesis (Davis & Kuttan, 2000). Immunity has been shown to be suppressed in cancer.…”
Section: Discussionmentioning
confidence: 99%
“…A diminuição no peso dos órgãos, especialmente do baço, seria um indicativo de toxicidade (Doi et. al, 1996;Davis e Kuttan, 2000 Acredita-se que a primeira fase do processo envolva a liberação de serotonina, histamina e cininas e a segunda fase seja mediada por prostaglandina e produtos da ciclooxigenase (Vinegar et al, 1969;Winter et al, 1962 No modelo murino de PIA, a injeção do óleo mineral na cavidade intraperitoneal de camundongos BALB/c induz peritonite crônica que é associada com níveis elevados e persistentes de IL-6. Uma alta porcentagem dos camundongos desenvolve plasmacitomas dependentes desta interleucina (Hinson et al, 1996).…”
Section: Resumo Dos Resultadosunclassified
“…Propriedades imunomoduladoras de várias plantas tem sido avaliadas (SaiRam et al, 1997;Borchers et al, 2000;Davis e Kuttan, 2000;Smit et al, 2000;Ross et al, 2001;Bin-Hafeez et al, 2003), visto que o sistema imune está envolvido na etiologia e nos mecanismos fisiopatológicos de muitas doenças (Lin et al, 2005).…”
Section: A Família Amaranthaceae E O Gênero Alternantheraunclassified
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