Immunomodulatory Effects of Probiotics in the Intestinal Tract

Delcenserie, Véronique; Martel, David; Lamoureux, M.; Amiot, J.; Boutin, Yvan; Roy, Denis

doi:10.21775/cimb.010.037

Cited by 105 publications

(17 citation statements)

References 117 publications

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“…The immune status was closely associated with inflammation which was mainly regulated by inflammatory cytokines. TNF, IL, and TGF are cytokines that play a vital role in body immunity (Delcenserie et al, 2008). In this study, a high level of CSM (CSM60 diet) in the diet markedly elevated the mRNA expression of IL-10, IL-8, C4, Hsp70, and IκB-α in the intestine and kidney.…”

Section: Discussionmentioning

confidence: 70%

Changes in Growth Performance, Nutrient Metabolism, Antioxidant Defense and Immune Response After Fishmeal Was Replaced by Low-Gossypol Cottonseed Meal in Golden Pompano (Trachinotus ovatus)

Qin

Wang

et al. 2021

Front. Mar. Sci.

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The present study was designed to elucidate the changing pattern of growth performance, nutrient metabolism, antioxidant defense, and immune response after fishmeal (FM) was replaced by cottonseed meal (CSM). Four isonitrogenous and isolipidic experimental diets (42.5% crude protein, 14.0% crude lipid) were formulated to replace 0% (CSM0 diet), 20% (CSM20 diet), 40% (CSM40 diet), and 60% (CSM60 diet) of the FM protein with CSM. Juvenile golden pompano (Trachinotus ovatus) with an initial body weight of 24.8 ± 0.02 g were fed each diet for 6 weeks. The results showed that compared with the control diet, significant differences were not found in the weight gain ratio, specific growth performance, and apparent digestibility of dry matter and protein after 20% FM was replaced by CSM. Higher CSM replacement markedly decreased the growth performance (P < 0.05). Moreover, the CSM20 and CSM40 diets did not depress the feed efficiency ratio and protein efficiency ratio compared with the CSM0 diet. Further exploring the physio-biochemical and molecular responses, the present study also showed that dietary 20–40% CSM replacement had no significant effect on altering the whole body, plasma nutrient contents, free amino acids, or whole-body fatty acid contents. Additionally, the CSM20 diet did not change the mRNA and protein phosphorylation levels of the key enzymes and regulators involved in target of rapamycin (TOR) and amino acid response (AAR) signaling, nutrient metabolism, immune response, and antioxidant defense. Higher CSM inclusion significantly varied the TOR and AAR signaling response, nutrient metabolism, immune response, and antioxidant defense. Based on the results, CSM could successfully replace 20% FM in the formulated diets for golden pompano. This study proposes the optimal inclusion level of CSM in the diet, which has an important significance in optimizing aquafeeds formulation.

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Section: Discussionmentioning

confidence: 70%

Changes in Growth Performance, Nutrient Metabolism, Antioxidant Defense and Immune Response After Fishmeal Was Replaced by Low-Gossypol Cottonseed Meal in Golden Pompano (Trachinotus ovatus)

Qin

Wang

et al. 2021

Front. Mar. Sci.

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“…The differentiation of naive T cells into different types of cell lines like TH-17, TH-2, TH-1, CD8+ repressor, and regulatory T cell depends upon the interaction of DC with specific pattern recognition factors. A study states that cytophage -bacteroides required for development of TH17 cells in lamina propria, which, in turn, maintains the balance between regulatory T-cell populations and TH-17 ( Foligne et al., 2007 ; Delcenserie et al., 2008 ; Zeuthen et al., 2008 ). Evidence proved that when germ-free mice were colonized with Bacteroides fragilis NCTC9343, an immense restoration was observed in the number of CD4+ CD45Rb T-cell populations.…”

Section: Gut Microbiota and Immune Modulationmentioning

confidence: 99%

Bacteriocin-Producing Probiotic Lactic Acid Bacteria in Controlling Dysbiosis of the Gut Microbiota

[]

Tiwari

2022

Front. Cell. Infect. Microbiol.

100

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Several strains of lactic acid bacteria are potent probiotics and can cure a variety of diseases using different modes of actions. These bacteria produce antimicrobial peptides, bacteriocins, which inhibit or kill generally closely related bacterial strains and other pathogenic bacteria such as Listeria, Clostridium, and Salmonella. Bacteriocins are cationic peptides that kill the target cells by pore formation and the dissipation of cytosolic contents, leading to cell death. Bacteriocins are also known to modulate native microbiota and host immunity, affecting several health-promoting functions of the host. In this review, we have discussed the ability of bacteriocin-producing probiotic lactic acid bacteria in the modulation of gut microbiota correcting dysbiosis and treatment/maintenance of a few important human disorders such as chronic infections, inflammatory bowel diseases, obesity, and cancer.

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“…When the bacterial populations are stabilized, and they image the adult's gut microbiome composition, the intestinal immune system is considered to be 'mature.' Usually, this takes place around the second year of life (Delcenserie et al, 2008). In the gut-lung axis conceptualization, probiotic bacteria settled in the gut wield an influence on respiratory allergies and can relieve the symptoms.…”

Section: Respiratory Allergy and The Oral Supplementation Of Probioticsmentioning

confidence: 99%

Impact of Probiotic Bacteria on Respiratory Allergy Disorders

Jakubczyk

Górska

2021

Front. Microbiol.

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Respiratory allergy is a common disease with an increased prevalence worldwide. The effective remedy is still unknown, and a new therapeutic approach is highly desirable. The review elaborates the influence of probiotic bacteria on respiratory allergy prevention and treatment with particular emphasis on the impact of the current methods of their administration – oral and intranasal. The background of the respiratory allergy is complex thus, we focused on the usefulness of probiotics in the alleviation of different allergy factors, in particular involved in pathomechanism, local hypersensitive evidence and the importance of epithelial barrier. In this review, we have shown that (1) probiotic strains may vary in modulatory potential in respiratory allergy, (2) probiotic bacteria are beneficial in oral and intranasal administration, (3) recombinant probiotic bacteria can modulate the course of respiratory allergy.

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Immunomodulatory Effects of Probiotics in the Intestinal Tract

Cited by 105 publications

References 117 publications

Changes in Growth Performance, Nutrient Metabolism, Antioxidant Defense and Immune Response After Fishmeal Was Replaced by Low-Gossypol Cottonseed Meal in Golden Pompano (Trachinotus ovatus)

Changes in Growth Performance, Nutrient Metabolism, Antioxidant Defense and Immune Response After Fishmeal Was Replaced by Low-Gossypol Cottonseed Meal in Golden Pompano (Trachinotus ovatus)

Bacteriocin-Producing Probiotic Lactic Acid Bacteria in Controlling Dysbiosis of the Gut Microbiota

Impact of Probiotic Bacteria on Respiratory Allergy Disorders

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