Immunomodulatory role of vitamin D in the pathogenesis of preeclampsia

Smith, Tyler A.; Kirkpatrick, Daniel R.; Kovilam, Oormila; Agrawal, Devendra K.

doi:10.1586/1744666x.2015.1056780

Cited by 34 publications

(32 citation statements)

References 44 publications

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“…More accurate analysis of the demographic data of the subjects showed a significant difference in the BMI values between the two groups, which were confirmed by other studies (3,6,20). The other demographic variable evaluated in the current study was age that had no significant difference between the two groups of pregnant women consistent with the results of the study by Zaroudi et al (31).…”

Section: Discussionsupporting

confidence: 91%

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Dietary Pattern in Patients with Preeclampsia in Fasa, Iran

et al. 2019

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Background: Preeclampsia is one of the causes of mortality and high-risk pregnancies that endangers the health of mothers in the developing countries. Objectives: The current study aimed at investigating the nutritional pattern in women with preeclampsia. Methods: The current cross sectional study was conducted on 182 pregnant women (82 patients with preeclampsia and 100 healthy subjects) selected using easy sampling in Fasa Vali-e-Asr Hospital in 2016. The dietary intake was evaluated using a semi-quantitative food frequency questionnaire and the intensity of day-night activities by a physical activity questionnaire. Anthropometric indicators were calculated according to standard guidelines, measurement, and body mass index. Dietary patterns were characterized by a factor analysis and its relationship with preeclampsia was investigated by logistic regression method. Results: Two unhealthy and healthy dietary patterns were identified among individuals. In the crude model and after adjusting the effect of confounding variables of unhealthy dietary patterns, no significant relationship was observed between dietary pattern and preeclampsia. In the fourth compare to the first quartile of the healthy dietary pattern, the chance of preeclampsia was 0.219 (95% CI: 0.090-0.528, P = 0.001) crude model and 0.178 (95% CI: 0.059-0.530, P = 0.002) adjusted model. Conclusions: The findings indicated that choosing a healthy dietary pattern was associated with a reduction in the risk of preeclampsia. Regarding these results, prevention of preeclampsia maybe possible by the healthy diet recommendation. The occurrence of complications in the mother, the fetus, and the baby in the future can also be prevented through the same way.

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Section: Discussionsupporting

confidence: 91%

“…the nutritional habits of individuals (18). Most research on nutritional patterns in pregnant women focuses on micronutrients, certain foods, or certain types of pregnancy (19)(20)(21).…”

Section: Introductionmentioning

confidence: 99%

Dietary Pattern in Patients with Preeclampsia in Fasa, Iran

et al. 2019

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“…Günümüzde ise hâlen etkin koruyucu ve terapötik yaklaşımlar yeterli değildir. 1,10,16,20,21 İleri yaş, obezite, ilk gebelik ve önceden PE öyküsü mevcudiyeti, PE risk etmenleridir. GDM ise ciddi/orta düzey PE ve gestasyonel hipertansiyon ile ilişkilendirilmektedir.…”

Section: Gebeli̇kte Vi̇tami̇n D Eksi̇kli̇ği̇ Ve Preeklampsi̇unclassified

Deleterious Outcomes of Vitamin D Deficiency and Toxicity on Maternal-Fetal, Infant and Child Health

Çağlayan¹,

Katlan²

2018

J Lit Pharm Sci

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“…Preeclampsia (PE) is a pregnancy-specific disorder that afects2-8% of all pregnancies (1) . Worldwide, PE is a significant health risk to both pregnant women and their unborn children (2) . The exact pathogenesis of PE is not yet fully understood (3) .…”

Section: Introductionmentioning

confidence: 99%

Obesity, Helicobacter pylori Infection and Preeclampsia: A triangle of Danger for pregnant women Running title: Helicobacter pylori Infection and Preeclampsia.

Shedid¹,

Mourad

2018

The Egypt. J. of Fert.y of Steri.

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Objectives:To determine the frequency of Helicobacter pylori (Hp) infection among primigravida and its relation to development of preeclampsia (PE). Patients and Methods:This cohort study included 146 primigravida evaluated prior to the 12th week gestational age, women who developed PE were categorized as PE group and a similar number of pregnant women free of hypertensive manifestations as control (No PE) group. All patients were evaluated for age and body mass index (BMI) and underwent Hp diagnosis workup including Urea breath test and Hp stool antigen testing.Results: Twenty-six women developed early and 47 developed late PE and 52 had mild, while 21 had severe PE. Development and severity of PE showed positive significant correlation with BMI. Sixty patients were Hp+; blood pressure measures at time of development of PE were significantly higher in Hp+ than in Hp-patients, irrespective of developing PE. Blood pressure measures and BMI showed positive significant correlation with Hp positivity. Statistical analysis defined high BMI as the significant independent predictor for development of PE. Conclusion:High BMI may underlie the development and severity of PE and is associated with Hp infection.

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Immunomodulatory role of vitamin D in the pathogenesis of preeclampsia

Cited by 34 publications

References 44 publications

Dietary Pattern in Patients with Preeclampsia in Fasa, Iran

Dietary Pattern in Patients with Preeclampsia in Fasa, Iran

Deleterious Outcomes of Vitamin D Deficiency and Toxicity on Maternal-Fetal, Infant and Child Health

Obesity, Helicobacter pylori Infection and Preeclampsia: A triangle of Danger for pregnant women Running title: Helicobacter pylori Infection and Preeclampsia.

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