Immunosuppressive activity of a monoterpene from Eucommia ulmoides

Immunosuppressive diacetylenes, ceramides and cerebrosides from Hydrocotyle leucocephala

“…Additionally, nine known compounds were identified by comparison of their spectroscopic data with literature values as follows: (À)-hinokinin 7 (da Silva et al, 2005), spinasterol 8 (Kojima et al, 1990), loliolide 9 (Okada et al, 1994), dehidrovomifoliol 10 ( Kato et al, 1977), 3-hydroxy-5a,6a-epoxy-7-megastigmen-9-one 11 (Duan et al, 2002), kaempferol-3-O-a-L-arabinopyranoside 12 (Väsange et al, 1997), quercetin-3-O-a-L-arabinopyranoside 13 (Almeida et al, 1998), quercetin-3-O-b-D-galactopyranoside 14 (Arisawa et al, 1984), and kaempferol-3-Ob-D-galactopyranoside 15 (Scharbert et al, 2004).…”

Alkamides and phenethyl derivatives from Aristolochia gehrtii

“…Extracts from the stems of A. gehrtii were fractionated by chromatographic column, followed by preparative TLC, to afford the known lignans 1-5 4,12-18 , sitosterol (6) 19 , benzoic acids 8, 9 20,21 , isoquinolone alkaloid 10 11,22,23 , phenethyl derivatives 12-17 7,[24][25][26][27] , and the terpene 18 28 10,29 . From gCOSY, gTOCSY, gHMQC, and gHMBC experiments, it was possible to assign more feasible δ values for carbons and hydrogens, including C-3, C-1' to C-6' and H-3, H-1' to H-6', than those previously described in the literature 29 .…”

Validation of a HPLC-tandem MS/MS method for pharmacokinetics study of (+)-pinoresinol-di-β-d-glucopyranoside from Eucommia ulmoides Oliv extract in rats’ plasma

“…Recently, the pharmacological studies proved that cortex of Eucommia ulmoides possess various activities such as antioxidant Yen and Hsieh, 2000;Chen et al, 2003;Lee et al, 2005;Zhang et al, 2005;Qu et al, 2006;Xu et al, 2010), antimicrobial and anti-inflammatory (Kim et al, 2009;Jiang et al, 2010;Tsai et al, 2010) and antihypertensive (Kwan et al, 2003(Kwan et al, , 2004Chang et al, 2005;Lang et al, 2005;Luo et al, 2010;Gu et al, 2011). The Eucommia ulmoides might also used as a remedy in case of protein differentiation (Li et al, 2000;Lee et al, 2004), immunosuppressive (Okada et al, 1994;Oshima et al, 1988;Zhu et al, 2009;Zhou et al, 2009), neuroprotective (Okada et al, 1994;Kwon et al, 2011) or inhibitory of osteoclast and osteoblastic apoptosis (Ha et al, 2003;Zhang et al, 2009;Lin et al, 2011). From the bark of the Eucommia ulmoides, various organic compounds were isolated such as lignans, phenylpropanoids, iridoid glycosides, flavonoid, polysaccharides and so on (Deyama et al, 2001).…”