Impact of a family history of hypertension on blood pressure levels during early and late adolescence.

Nishiyama, Seiichi; Kodama, Koji; Sumimoto, Takumi; Hiwada, Kunio; Kokubu, Tatsuo

doi:10.1253/jcj.53.13

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…Regional, racial, and local differences observed among various published studies were due to the difference in genetic factors, body constitution, dietary habits, personal preferences, lifestyle, habitation, and existing disease pattern in the concerned society [ 11 , 25 ]. However, a thread of uniformity, resonance, and reflectiveness always exists while assessing the underlying causes.…”

Section: Discussionmentioning

confidence: 99%

The Association Between Body Mass Index and Parental History of Hypertension Among Young Indian Adults

Jain¹,

Gumashta²,

Gumashta³

et al. 2023

Cureus

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Background: Hypertension is a disease of multifactorial etiology. Individuals with parental history of hypertension (PHH) have also been observed to be at an increased risk of developing hypertension in their adult life. However, there is a dearth of studies among youth. Obesity is one of the risk factors, and studies conducted among adults of all age groups have observed that there is a highly significant correlation between hypertension and body mass index (BMI). Hence, the association between the two factors, viz., parental history of hypertension and BMI, among the young Indian male and female population was analyzed in this study. Method: This cross-sectional study conducted in Central India comprised 100 young adults between 18 and 25 years of age. On the basis of parental history of hypertension, the subjects were divided into two groups: group 1 comprised youth with parental history of hypertension and group 2 comprised youth without parental history of hypertension, involving 32 and 68 subjects in each of these groups, respectively. Anthropometric measurements were done using standard methods, and BMI was calculated. Statistical analysis was done using Epi Info software. Results: The study subjects in both groups were comparable in age. The mean age of the study participants was 19.32 years and 19.45 years in group 1 and group 2, respectively. The study did not find any association between BMI and parental history of hypertension. Conclusion: The association between parental history of hypertension and BMI, the non-modifiable and modifiable independent risk factors, respectively, needs to be further explored in light of the iceberg phenomenon, multifactorial causation, and natural history of disease. It is worth mentioning that parental history of hypertension and other risk factors should be considered even if the BMI is normal as per Asian Indian cutoff levels.

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Section: Discussionmentioning

confidence: 99%

The Association Between Body Mass Index and Parental History of Hypertension Among Young Indian Adults

Jain¹,

Gumashta²,

Gumashta³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

Family History of Hypertension and Blood Pressure in a Screened Cohort.

et al. 2001

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We sought to determine whether a family history of hypertension is quantitatively associated with the prevalence of hypertension and blood pressure in a screened cohort. Clinical data and family (parents and siblings) histories regarding hypertension were collected from 9,914 individuals (probands) who were interviewed and examined during a one-day clinic by the Okinawa General Health Maintenance Association in 1997. We used logistic analysis to calculate odds ratios with adjustments for age, sex, body mass index, total cholesterol, presence of diabetes mellitus, alcohol use, cigarette smoking, and status of physical exercise. The age- and sex-adjusted hypertension prevalences in probands were 29.0% for those with 1 family member with a history of hypertension (n=2,112), 37.6% for those with 2 hypertensive family members (n=374), and 47.3% for those with 3 or more hypertensive family members (n=68). In contrast, only 16.4% of probands who reported no family history of hypertension (n=7,360) were hypertensive themselves. The trend of the prevalence according to the number of family members with a history of hypertension was significantly positive (p=0.003). The adjusted odds ratios (95% confidence interval) of hypertension were 2.74 (2.43-3.10) for 1 member, 4.62 (3.62-5.90) for 2 members, and 6.04 (3.51-10.4) for 3 or more members with a history of hypertension. In patients without antihypertensive medication (n=9,009), systolic/diastolic blood pressure (mean +/- SD) was 121 +/- 17/75 +/- 11 for 1 member, 124 +/- 18/77 +/- 12 for 2 members, and 127 +/- 17/78 +/- 11 for 3 or more members with a history of hypertension. In contrast, the mean systolic/diastolic blood pressure of probands who reported no family history of hypertension (n=7,360) was 119 +/- 15/74 +/- 10 mmHg, which was significantly (p<0.05) lower than that of any of the groups with hypertensive family members. In conclusion, an increase in the number of family members with hypertension was associated with an increasing prevalence of hypertension and blood pressure in the probands, independent of conventional risk factors for hypertension. Family members of hypertensive subjects may need to be treated in primary prevention efforts related to hypertension.

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Impact of a family history of hypertension on blood pressure levels during early and late adolescence.

Cited by 2 publications

References 15 publications

The Association Between Body Mass Index and Parental History of Hypertension Among Young Indian Adults

The Association Between Body Mass Index and Parental History of Hypertension Among Young Indian Adults

Family History of Hypertension and Blood Pressure in a Screened Cohort.

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