Impact of Blood Transfusions on Survival and Recurrence in Colorectal Cancer Surgery

Guňka, I; Dostalík, J; Martínek, L; Guňková, P; Mazur, Miloslav

doi:10.1007/s12262-012-0427-6

Cited by 23 publications

(17 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Other factors such as a greater number of stage I patients and a higher rate of a laparoscopic approach in the screening group (although not statistical significant) could have had an impact on the reduced need for transfusion. On the other hand, perioperative transfusion is an independent risk factor for a worse oncological outcome (13,14). The nutritional status is a key factor in cancer patients undergoing surgery (15).…”

Section: Discussionmentioning

confidence: 99%

The impact of screening on short-term outcome after surgery for colorectal cancer

Sebastian¹,

Courtier²,

Macià³

et al. 2017

Rev Esp Enferm Dig

View full text Add to dashboard Cite

Aim: To investigate the influence of a screening program on the short-term outcome of patients undergoing surgery for colorectal cancer.Methods: Between April 2010 and December 2012 patients diagnosed with colorectal cancer via the screening program (n = 80) were compared with patients diagnosed elsewhere (n = 106). Only patients of ≥ 50 and ≤ 69 years of age diagnosed outside the program were selected as controls. The clinical variables included age, sex, American Society of Anesthesiologists (ASA) status, Charlson index, preoperative hemoglobin and serum albumin levels, surgical approach, tumor location and stage, perioperative transfusion and postoperative morbidity. A multivariate analysis was used to identify variables independently associated with outcome.Results: There were no significant differences with regard to age, sex and ASA status. Preoperative hemoglobin (14.1 ± 1.6 g/ dl vs 12.3 ± 2.3 g/dl; p < 0.001) and serum albumin (4.45 ± 0.26 g/dl vs 4.0 ± 0.6 g/dl; p < 0.001) levels were significantly higher in the screening group. The overall morbidity was significantly lower in the screening group (38.8% vs 63.2; p < 0.001) and mainly related to a higher rate of Clavien-Dindo grade II complications in controls. There were no differences with regard to wound infection, postoperative ileus, anastomotic leakage or reoperations. The median length of hospital stay was shorter in the screening group (6 vs 9 days; p = 0.003). Multivariate analysis showed that diagnosis outside the screening program, type of surgical procedure, open surgery and Charlson index were independent risk factors for postoperative complications.Conclusions: The diagnosis of colorectal cancer via the screening program is associated with a lower rate of postoperative minor complications and a shorter hospital stay.

show abstract

Section: Discussionmentioning

confidence: 99%

The impact of screening on short-term outcome after surgery for colorectal cancer

Sebastian¹,

Courtier²,

Macià³

et al. 2017

Rev Esp Enferm Dig

View full text Add to dashboard Cite

show abstract

“…Our study pointed out association between fasting time and need for blood transfusion. It is important remember that blood transfusion, among colorectal cancer patients, have been associated with increased length of stay, morbidity, recurrence of tumor, decreased long term survival and death (15)(16)(17) . Therefore, it can be deduced that, even if fasting is necessary at some time due to the health condition of gastrointestinal tumor patients, the excessive extension of this fasting time can compromise the recovery, prolongs the hospitalization and increases the chances of complications and even death.…”

Section: The Projects Enhanced Recovery After Surgery (Eras) and The mentioning

confidence: 99%

Perioperative fasting time among cancer patients submitted to gastrointestinal surgeries

Pereira

Turrini

Poveda

2017

Rev. esc. enferm. USP

View full text Add to dashboard Cite

Objective:To identify the length of perioperative fasting among patients submitted to gastrointestinal cancer surgeries. Method: Retrospective cohort study, developed by consulting the medical records of 128 patients submitted to gastrointestinal cancer surgeries. Results: The mean of total length of fasting was 107.6 hours. The total length of fasting was significantly associated with the number of symptoms presented before (p=0.000) and after the surgery (p=0.007), the length of hospital stay (p=0.000), blood transfusion (p=0.013), nasogastric tube (p=0.001) and nasojejunal tube (p=0,003), postoperative admission at ICU (p=0.002), postoperative death (p=0.000) and length of preoperative fasting (p=0.000). Conclusion: The length of fasting is associated with complications that affect the quality of the patients' postoperative recovery and nurses' work. The nursing team should be alert to this aspect and being responsible for overseeing the patients' interest, should not permit the unnecessary extension of fasting.

show abstract

“…15, 16, 17 The highest rates of new recurrence were seen in "Pre-Transfusion Protocol No Blood," which had new recurrence in 17.8% of patients, and the lowest percentage of new recurrence was 7.7% for "Pre-Transfusion Protocol Blood. "…”

Section: Discussionmentioning

confidence: 99%

Restrictive blood transfusion protocol in malignant upper gastrointestinal and pancreatic resections patients reduces blood transfusions with no increase in patient morbidity

Wehry

Agle

Philips

et al. 2015

The American Journal of Surgery

View full text Add to dashboard Cite

Background The purpose of this study was to determine the impact of a restrictive blood transfusion protocol on the number of transfusions performed and the related effect on patient morbidity. Methods A cohort study was performed using our prospective database with information from 01/01/2000–06/01/2013. The restrictive blood transfusion protocol was implemented in 9/2011, so this date served as the separation point for the date of operation criteria. Results For the study, 415 patients undergoing operation for an abdominal malignancy were reviewed. Following the restrictive blood transfusion protocol the percentage of patients that received blood dropped from 35.6% to 28.3%. The percentage of patients that experienced perioperative complication was significantly higher in transfused patients compared to those that did not receive blood(p=0.0001). There was no statistical significance observed between the four groups for the length of stay at the hospital following their procedure. Conclusion The restrictive blood transfusion protocol resulted in a reduction of the percentage of patients transfused, and there was no evidence to suggest that it negatively impacted the outcomes of patients in this group.

show abstract

Impact of Blood Transfusions on Survival and Recurrence in Colorectal Cancer Surgery

Cited by 23 publications

References 20 publications

The impact of screening on short-term outcome after surgery for colorectal cancer

The impact of screening on short-term outcome after surgery for colorectal cancer

Perioperative fasting time among cancer patients submitted to gastrointestinal surgeries

Restrictive blood transfusion protocol in malignant upper gastrointestinal and pancreatic resections patients reduces blood transfusions with no increase in patient morbidity

Contact Info

Product

Resources

About